Results 181 to 190 of about 379,930 (351)

Painless Multiple Cranial Neuropathies due to Symptomatic Bone Marrow Metastasis in First Diagnosis of Advanced Stage Breast Cancer: A Case Report

Siriporn Lin, Jarukit Tantipisit, Nattha Sanghan, Pat Korathanakhun   +3 more
openalex   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Figure S9 from <i>In Silico</i> Digital Twins of Bone Metastasis Enable Investigation of Tumor Progression and Therapy Response

Luca Marsilio, Sergio Barrios, Stefan Maksimovic, Alice Maccarini, Elisa Serafini, Michele Grimaldi, Thomas Heyman, Pietro Cerveri, Stefano Casarin, Eleonora Dondossola   +9 more
openalex   +1 more source

Targeting the Hyperglycemic Pre‐Metastatic Niche to Prevent Breast Cancer Bone Metastasis: Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
Abstract The recent pioneering study by Ye et al. (Adv Sci. 2025;12(37):e0504924) provides compelling evidence that systemic hyperglycemia orchestrates a pre‐metastatic niche (PMN) in bone, promoting breast cancer metastasis and identifying Receptor for Advanced Glycation End‐products (RAGE) inhibition as a viable therapeutic strategy.
DuJiang Yang, Jiexiang Yang, GuoYou Wang
wiley   +1 more source

Recognition of the novel items for prediction of bone metastasis in colorectal cancer. [PDF]

Front Oncol
Chen M, Wang X, Bai S, Lan N, Wang J, Chen Y, Gao Y, Wang W, Shang X, Jiao M, Zhang X, Li W, Wu F, Liu W, Hu F, Chen L, Ren J.   +16 more
europepmc   +1 more source

Recent Progress in Mechanoluminescence for Multi‐Dimensional Stress Monitoring

Advanced Science, EarlyView.
Multi‐dimensional stress visualization technology (0D point detection, 1D linear distribution, 2D planar imaging, 3D volume reconstruction) has become a focus of attention in the field of stress sensing. The transition from “points” to “multi‐dimensional spatial fields” facilitates real‐time, in situ, and high‐resolution visualization of stress ...
Xiuxia Yang, Ting Wang, Lei Zhao, Xuhui Xu   +3 more
wiley   +1 more source

Aberrant lipid metabolism reshapes the immune landscape in bone metastasis of nasopharyngeal carcinoma. [PDF]

J Immunother Cancer
Feng Y, Wang H, Zhu Z, Deng W, He X, Yao Y, Song M, Peng X, Lin Y, Cai L.   +9 more
europepmc   +1 more source

Supplementary Figure 2 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

, 2023
Neng‐Yu Lin, Jian‐Jr Lee, Syue‐Ting Chen, Jung‐An Lin, Chia‐Hsuan Lin, Hsuan‐Yu Lin, Yong-Han Su, Cheng‐Chang Chen, Mei‐Chun Lin, Ching‐Ying Kuo, Min‐Chuan Huang   +10 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Hypercalcemia associated with relapsed medulloblastoma due to bone metastasis: illustrative case. [PDF]

J Neurosurg Case Lessons
Ito R, Kanamori M, Shimoda Y, Irie M, Niizuma H, Watanabe H, Watanabe M, Kanemura Y, Kikuchi A, Endo H.   +9 more
europepmc   +1 more source