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Current Osteoporosis Reports, 2019
This review provides an update on the recent literature describing the role of microRNAs (miRNAs) in cancer formation and bone metastasis. We confined our focus on osteosarcoma, breast cancer, prostate cancer, and epithelial-mesenchymal transition.In all areas covered, major discoveries on the role of miRNAs in tumorigenesis and metastasis have been ...
Eric, Hesse, Hanna, Taipaleenmäki
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This review provides an update on the recent literature describing the role of microRNAs (miRNAs) in cancer formation and bone metastasis. We confined our focus on osteosarcoma, breast cancer, prostate cancer, and epithelial-mesenchymal transition.In all areas covered, major discoveries on the role of miRNAs in tumorigenesis and metastasis have been ...
Eric, Hesse, Hanna, Taipaleenmäki
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Ugeskrift for laeger, 1989
Bone metastases are frequently one of the first signs of disseminated disease in cancer patients. In the majority of patients, the primary tumour originates from the breast, prostate or lungs. Even although the prognosis is serious, a proportion of the patients will survive for several years and will thus require active treatment.
O S, Nielsen, H, Skovgaard Poulsen
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Bone metastases are frequently one of the first signs of disseminated disease in cancer patients. In the majority of patients, the primary tumour originates from the breast, prostate or lungs. Even although the prognosis is serious, a proportion of the patients will survive for several years and will thus require active treatment.
O S, Nielsen, H, Skovgaard Poulsen
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Bone resorption and bone metastasis risk
Medical Hypotheses, 2018Breast cancer tumors have a tendency to metastasize to the bone. After development of a bone metastasis, the median survival time is 40 months. Currently, little is known about the modifiable risk factors for developing bone metastases in women diagnosed with breast cancer. One possible modifiable risk factor is increased bone resorption.
Katlynn M, Mathis +5 more
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Cancer, 1997
Solid cancers metastasize to bone by a multistep process that involves interactions between tumor cells and normal host cells. Some tumors, most notably breast and prostate carcinomas, grow avidly in bone because the bone microenvironment provides a favorable soil.
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Solid cancers metastasize to bone by a multistep process that involves interactions between tumor cells and normal host cells. Some tumors, most notably breast and prostate carcinomas, grow avidly in bone because the bone microenvironment provides a favorable soil.
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2018
Bone metastases are a frequent complication of advanced cancer. Interactions between cancer cells and marrow stromal cells and bone turnover mechanisms are crucial in metastases growth and the pathogenesis of bone damage. Metastatic tumour cells stimulate the bone remodelling and indirectly induce the osteocytes to release several growth factors that ...
Carlo della Rocca, Claudio Di Cristofano
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Bone metastases are a frequent complication of advanced cancer. Interactions between cancer cells and marrow stromal cells and bone turnover mechanisms are crucial in metastases growth and the pathogenesis of bone damage. Metastatic tumour cells stimulate the bone remodelling and indirectly induce the osteocytes to release several growth factors that ...
Carlo della Rocca, Claudio Di Cristofano
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Hepatology, 2020
Bone is the second most frequent site of metastasis for HCC, which leads to an extremely poor prognosis. HCC bone metastasis is typically osteolytic, involving the activation of osteoclasts.
Zhao Huang +22 more
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Bone is the second most frequent site of metastasis for HCC, which leads to an extremely poor prognosis. HCC bone metastasis is typically osteolytic, involving the activation of osteoclasts.
Zhao Huang +22 more
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ACS Nano, 2019
Bone metastasis, a clinical complication of patients with advanced breast cancer, seriously reduces the quality of life. To avoid destruction of the bone matrix, current treatments focus on inhibiting the cancer cell growth and the osteoclast activity ...
Wentong Sun +10 more
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Bone metastasis, a clinical complication of patients with advanced breast cancer, seriously reduces the quality of life. To avoid destruction of the bone matrix, current treatments focus on inhibiting the cancer cell growth and the osteoclast activity ...
Wentong Sun +10 more
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1971
To the Editor.— Suffett et al ( 215 :120, 1971) in reference to an article by Reichbach et al 1 on osseous metastases of hepatoma reported a tumor that had metastasized to a rib. They suggest that osseous metastases from hepatomas are very uncommon. This is not really the case, as various authors 2-5 have reported an incidence ranging from 1.6% to 12%
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To the Editor.— Suffett et al ( 215 :120, 1971) in reference to an article by Reichbach et al 1 on osseous metastases of hepatoma reported a tumor that had metastasized to a rib. They suggest that osseous metastases from hepatomas are very uncommon. This is not really the case, as various authors 2-5 have reported an incidence ranging from 1.6% to 12%
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JAMA: The Journal of the American Medical Association, 1981
R, Zouari +4 more
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R, Zouari +4 more
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Bone metastasis consensus statement
International Journal of Radiation Oncology*Biology*Physics, 1992Bates, T. +5 more
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