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Ugeskrift for laeger, 1989
Bone metastases are frequently one of the first signs of disseminated disease in cancer patients. In the majority of patients, the primary tumour originates from the breast, prostate or lungs. Even although the prognosis is serious, a proportion of the patients will survive for several years and will thus require active treatment.
O S, Nielsen, H, Skovgaard Poulsen
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Bone metastases are frequently one of the first signs of disseminated disease in cancer patients. In the majority of patients, the primary tumour originates from the breast, prostate or lungs. Even although the prognosis is serious, a proportion of the patients will survive for several years and will thus require active treatment.
O S, Nielsen, H, Skovgaard Poulsen
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Bone resorption and bone metastasis risk
Medical Hypotheses, 2018Breast cancer tumors have a tendency to metastasize to the bone. After development of a bone metastasis, the median survival time is 40 months. Currently, little is known about the modifiable risk factors for developing bone metastases in women diagnosed with breast cancer. One possible modifiable risk factor is increased bone resorption.
Katlynn M, Mathis +5 more
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New England Journal of Medicine, 2004
Extract: Cancer frequently spreads to bone, a process termed bone metastasis. Up to 70% of patients with breast cancer or prostate cancer, and 15 to 30% of patients with lung, colon, bladder or kidney cancer develop bone metastasis. Once tumors go to bone, such as in patients with breast cancer or prostate cancer, they are incurable, and only 20% of ...
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Extract: Cancer frequently spreads to bone, a process termed bone metastasis. Up to 70% of patients with breast cancer or prostate cancer, and 15 to 30% of patients with lung, colon, bladder or kidney cancer develop bone metastasis. Once tumors go to bone, such as in patients with breast cancer or prostate cancer, they are incurable, and only 20% of ...
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Cancer, 1997
Solid cancers metastasize to bone by a multistep process that involves interactions between tumor cells and normal host cells. Some tumors, most notably breast and prostate carcinomas, grow avidly in bone because the bone microenvironment provides a favorable soil.
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Solid cancers metastasize to bone by a multistep process that involves interactions between tumor cells and normal host cells. Some tumors, most notably breast and prostate carcinomas, grow avidly in bone because the bone microenvironment provides a favorable soil.
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2018
Bone metastases are a frequent complication of advanced cancer. Interactions between cancer cells and marrow stromal cells and bone turnover mechanisms are crucial in metastases growth and the pathogenesis of bone damage. Metastatic tumour cells stimulate the bone remodelling and indirectly induce the osteocytes to release several growth factors that ...
Carlo della Rocca, Claudio Di Cristofano
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Bone metastases are a frequent complication of advanced cancer. Interactions between cancer cells and marrow stromal cells and bone turnover mechanisms are crucial in metastases growth and the pathogenesis of bone damage. Metastatic tumour cells stimulate the bone remodelling and indirectly induce the osteocytes to release several growth factors that ...
Carlo della Rocca, Claudio Di Cristofano
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JAMA: The Journal of the American Medical Association, 1971
To the Editor.— Suffett et al ( 215 :120, 1971) in reference to an article by Reichbach et al 1 on osseous metastases of hepatoma reported a tumor that had metastasized to a rib. They suggest that osseous metastases from hepatomas are very uncommon. This is not really the case, as various authors 2-5 have reported an incidence ranging from 1.6% to 12%
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To the Editor.— Suffett et al ( 215 :120, 1971) in reference to an article by Reichbach et al 1 on osseous metastases of hepatoma reported a tumor that had metastasized to a rib. They suggest that osseous metastases from hepatomas are very uncommon. This is not really the case, as various authors 2-5 have reported an incidence ranging from 1.6% to 12%
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Nanomaterials for bone metastasis
Journal of Controlled ReleaseBone metastasis, a prevalent occurrence in primary malignant tumors, is often associated with a grim prognosis. The bone microenvironment comprises various coexisting cell types, working together in a coordinated manner. This dynamic microenvironment plays a pivotal role in the initiation and progression of bone metastases.
Xinyan, Hao +9 more
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JAMA: The Journal of the American Medical Association, 1981
R, Zouari +4 more
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R, Zouari +4 more
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Bone metastasis consensus statement
International Journal of Radiation Oncology*Biology*Physics, 1992Bates, T. +5 more
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Science Signaling, 2013
Signaling by the growth factor TGF-β2 prevents the growth of squamous carcinoma that metastasizes to the bone.
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Signaling by the growth factor TGF-β2 prevents the growth of squamous carcinoma that metastasizes to the bone.
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