Results 101 to 110 of about 3,933,159 (293)

Effects of smoking on tibial and radial bone mass and strength may diminish with age [PDF]

, 2010
Purpose: The purpose of the study was to assess the effect of cigarette smoking on indicators of bone strength across a wide age range, controlling for physical activity and neuromuscular performance. Methods:Weconducted a cross-sectional study with 41
Rittweger, Jörn, Wüst, Robert C.I., Morse, Christopher I., Wilks, Désirée C., Morse, Christopher I, Wüst, Rob C I, Degens, Hans, Winwood, Keith L., Wilks, Désirée C, Wüst, Rob C I; id_orcid, Winwood, Keith, Wüst, Rob   +11 more
core   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Factors associated with low bone mineral density at diagnosis in pediatric Crohn’s disease: a large retrospective cohort study

BMC Gastroenterology
Background Crohn’s disease can adversely affect bone mineral density and low bone mineral density is a concern in pediatric Crohn’s disease. We evaluated factors associated with below-average bone mineral density (z-score ≤ − 1.0) at Crohn’s disease ...
Hansol Kim, Yoon Zi Kim, Seon Young Kim, Yon Ho Choe, Mi Jin Kim   +4 more
doaj   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

Mineral maturity and crystallinity index are distinct characteristics of bone mineral [PDF]

, 2010
The purpose of this study was to test the hypothesis that mineral maturity and crystallinity index are two different characteristics of bone mineral. To this end, Fourier transform infrared microspectroscopy (FTIRM) was used.
Delmas, Pierre D., Delmas, Pierre, D., Boivin, Georges, Panczer, Gérard, Rey, Christian, Farlay, Delphine   +5 more
core   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Bound Water as a Reinforcing Element for Ultra‐Strong Polyacrylamide

Advanced Science, EarlyView.
Rather than acting as a conventional plasticizer, bound water serves as a reinforcing element in polyacrylamide by constructing strong PAM–water–PAM hydrogen‐bond networks. This water‐mediated architecture delivers ultra‐high mechanical strength and exceptional flame resistance, redefining the role of water in polymer reinforcement.
Sirawit Pruksawan, Nannan Li, Zehuang Lin, Jianwei Zheng, Terence Jun En Loh, Yi Ting Chong, Junhua Kong, Xunan Hou, Xian Jun Loh, Chaobin He, FuKe Wang   +10 more
wiley   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Bone fractures after menopause [PDF]

, 2010
Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength.PubMed searches were performed, for studies of the ...
Ralston, Stuart H., J. L. Evers, Baird, D. T., A. Volpe, Ralston, S.H., Brandi, M.L., G. Benagiano, Brandi, Maria Luisa, S. H. Ralston, P.G. Crosignani, P. Bouchard, Rizzoli, R., ESHRE Capri Workshop Grp, Barlow, David H., La Vecchia, C., Negri, E., M. L. Brandi, P. G. Crosignani, Rizzoli, Rene, Benagiano, G., S. E. Papapoulos, Evers, J.L.H., D. H. Barlow, J. Collins, C. La Vecchia, Baird, D.T., Negri, Eva, Crosignani, P. G., Papapoulos, Socrates E., Glasier, A., R. Rizzoli, Barlow, D.H., A. Glasier, Vecchia, C. la, Collins, J., D. T. Baird, Volpe, A., Bouchard, P., Crosignani, P.G., Bouchard, Philippe, ?, ?, Papapoulos, S.E., E. Negri, Evers, J. L. H.   +43 more
core   +1 more source