Results 21 to 30 of about 570,840 (405)

Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture

PLoS ONE, 2018
Low bone mineral density (BMD) leads to osteoporosis, and is a risk factor for bone fractures, including stress fractures. Using data from UK Biobank, a genome-wide association study identified 1,362 independent SNPs that clustered into 899 loci of which
Stuart K. Kim
semanticscholar   +1 more source

Factors associated with low bone density in patients referred for assessment of bone health [PDF]

, 2013
Background: To identify factors that predict low bone mineral density (BMD) in pediatric patients referred for dual-energy x-ray absorptiometry assessments.
Giancaterino, Courtney, Gordon, Catherine Mason, Melvin, Patrice, Topor, Lisa Michelle   +3 more
core   +1 more source

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra, Anne-Margriet Huisman, Ans C.M. Oostveen, Ben A.C. Dijkmans, Chris E.D. de Laet, de Nijs RN, Erik Buskens, George A.W. Bruyn, Johannes W.G. Jacobs, Johannes W.J. Bijlsma, Michel BA, Piet P.M.M. Geusens, Roland F.J. Laan, Ron N.J. de Nijs, Willem F. Lems   +14 more
core   +4 more sources

Prediction of bone mineral density in CT using deep learning with explainability

Frontiers in Physiology, 2023
Bone mineral density (BMD) is a key feature in diagnosing bone diseases. Although computational tomography (CT) is a common imaging modality, it seldom provides bone mineral density information in a clinic owing to technical difficulties.
Jeong-Woon Kang, Chunsu Park, Dong-Eon Lee, Jae-Heung Yoo, MinWoo Kim   +4 more
doaj   +1 more source

The use of a noninvasive and nondestructive method, microcomputed tomography, to evaluate the anti-osteoporotic activity of erxian decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosis [PDF]

, 2009
Aim of the study: The anti-osteoporotic activity of Erxian Decoction, a Chinese medicinal formula, in a rat model of menopausal osteoporosis was evaluated by microcomputed tomography (microCT).
Lai, YM, Lau, ASL, Ng, TB, Sze, SCW, Tong, Y, Yow, CMN, Zhang, YB, Zhong, LLD   +7 more
core   +1 more source

Tibial dyschondroplasia and bone mineral density [PDF]

Revista Brasileira de Ciência Avícola, 2004
This study was carried out at Faculdade de Medicina Veterinária e Zootecnia, UNESP, Botucatu-SP, Brazil. The aim was to establish the normal values of bone mineral density (BMD) expressed in millimeters of aluminum in the tibia of broiler chickens using optical densitometry of radiographs.
Paz, Ibiara Correia de Lima Almeida, Mendes, AA, Takita, TS, Vulcano, LC, Guerra, PC, Wescheler, FS, Garcia, RG   +6 more
openaire   +7 more sources

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus [PDF]

, 2017
Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS meta-analysis of total-body lean
Ackert-Bicknell, C. (Cheryl), Ahluwalia, T.S. (Tarunveer Singh), Bagos, P.G. (Pantelis G.), Bisgaard, H. (Hans), Boer, C.G. (Cindy G.), Bonewald, L.F. (Lynda F.), Bønnelykke, K. (Klaus), Chesi, A. (Alessandra), Demissie, S. (Serkalem), Dimou, N.L. (Niki L.), Duque, G. (Gustavo), Eerden, B.C.J. (Bram) van der, Evangelou, E. (Evangelos), Evans, D.M. (David), Gautvik, K.M. (Kaare), Ghanbari, M. (Mohsen), Gorski, J.P. (Jeffrey P.), Grant, S.F.A. (Struan), Heppe, D.H.M. (Denise), Hsu, Y.-H. (Yi-Hsiang), Jaddoe, V.W.V. (Vincent), Karasik, D. (David), Kemp, J.P. (John), Kiel, D.P. (Douglas P.), Kreiner, E. (Eskil), Maurano, M.T. (Matthew T.), Medina-Gomez, M.C. (Carolina), Peppel, J. (Jeroen) van de, Raastad, T. (Truls), Reppe, S. (Sjur), Rivadeneira Ramirez, F. (Fernando), Tobias, J.H. (Jon), Uitterlinden, A.G. (André), Zemel, B.S. (Babette S.)   +33 more
core   +1 more source

The relationship between adiposity, bone density and microarchitecture is maintained in young women irrespective of diabetes status [PDF]

, 2017
Background: The relationship between bone health and adiposity and how it may be affected in people with chronic metabolic conditions is complex. Methods: 17 women with Type 1 diabetes mellitus (T1DM) and 9 age-matched healthy women with a median ...
Abdalrahaman, N., Ahmed, S.F., Drummond, R., Foster, J.E., Lindsay, R.S., Mccomb, C., McKay, G.A., Perry, C.G.   +7 more
core   +1 more source

Bone mineral density: testing for osteoporosis.

Australian Prescriber, 2016
Primary osteoporosis is related to bone loss from ageing. Secondary osteoporosis results from specific conditions that may be reversible. A thoracolumbar X-ray is useful in identifying vertebral fractures, and dual energy X-ray absorptiometry is the ...
Angela Sheu, Terry Diamond
semanticscholar   +1 more source

Bone mineral density and body composition in girls with idiopathic central precocious puberty before and after treatment with a gonadotropin-releasing hormone agonist

Clinics, 2012
OBJECTIVES: Idiopathic central precocious puberty and its postponement with a (gonadotropin-releasing hormone) GnRH agonist are complex conditions, the final effects of which on bone mass are difficult to define. We evaluated bone mass, body composition,
Sandra B. Alessandri, Francisco de A. Pereira, Rosângela A. Villela, Sonir R. R. Antonini, Paula C. L. Elias, Carlos E. Martinelli Jr., Margaret de Castro, Ayrton C. Moreira, Francisco J. A. de Paula   +8 more
doaj   +1 more source