Results 61 to 70 of about 186,000 (307)

Inter-species variation in bone mineral [PDF]

, 2011
Bone is a complex heterogeneous composite material with organic and inorganic components. The inorganic component; bone mineral, is a poorly crystalline, non-stoichiometric form of calcium hydroxylapatite.
Beckett, Sophie
core  

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Effects of FGF21 overexpression in osteoporosis and bone mineral density: a two-sample, mediating Mendelian analysis

Frontiers in Endocrinology
ObjectiveFibroblast growth factor 21 (FGF21) is a secreted protein that regulates body metabolism. In recent years, many observational studies have found that FGF21 is closely related to bone mineral density and osteoporosis, but the causal relationship ...
Jingjing Liu, Jun Jiang, Yunjia Li, Qiaojun Chen, Ting Yang, Yanfa Lei, Zewei He, Xiaowei Wang, Qiang Na, Changtao Lao, Xinlei Luo, Lirong Yang, Zhengchang Yang   +12 more
doaj   +1 more source

Measurement bone mineral density (BMD) of patients with beta thalassemia

Data in Brief, 2018
The aim of the study is determining bone mineral density (BMD) of Patients with beta thalassemia in order to find the prevalence and related factors on the conditions.
Sakineh Abbasi, Jafar Fatahi Asl, Leila Moein Zadeh, Mohammad Mirdoraghi   +3 more
doaj   +1 more source

Factors associated with bone mineral density in adults: a cross-sectional population-based study

Revista da Escola de Enfermagem da USP, 2020
Objective: This study aimed to analyze the association between lumbar spine, femoral neck, total hip bone mineral density (biophysical bone health assessment parameter), and sociodemographic, anthropometric, behavioral, and health condition factors in ...
Kátia Josiany Segheto, Leidjaira Lopes Juvanhol, Cristiane Junqueira de Carvalho, Danielle Cristina Guimarães da Silva, Adriana Maria Kakehasi, Giana Zarbato Longo   +5 more
doaj   +1 more source

The global, regional, and national burden attributable to low bone mineral density, 1990–2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021

BACKGROUND: Fractures related to osteoporosis and low bone mineral density lead to substantial morbidity, mortality, and cost to individuals and health systems.
GBD 2021 Low Bone Mineral Density Collaborators
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Testosterone is an independent determinant of bone mineral density in men with type 2 diabetes mellitus. [PDF]

, 2011
Although many reports have elucidated pathophysiological characteristics of abnormal bone metabolism in patients with type 2 diabetes mellitus (DT2), determinants of bone mineral density (BMD) in patients with DT2 are still ...
Tamara Sharshakova, Igor Sanec, Vasilkova, Olga, Noboru Takamura, Olga Vasilkova, Mokhort, Tatiana, Sharshakova, Tamara, Hayashida, Naomi, Tatiana Mokhort, Naomi Hayashida, Takamura, Noboru, Sanec, Igor   +11 more
core   +1 more source

Bone mineral density, vitamin D and anticonvulsant therapy [PDF]

Arquivos de Neuro-Psiquiatria, 2000
The aim of this study was to assess bone mineral density and vitamin D metabolism in patients on chronic anticonvulsant therapy. METHODS: Sixty-nine men, outpatients on chronic anticonvulsant therapy, who had been treated for at least 5 years, were ...
SILVANA FILARDI, CARLOS A.M. GUERREIRO, LUIS ALBERTO MAGNA, JOÃO FRANCISCO MARQUES NETO   +3 more
doaj   +1 more source