Results 51 to 60 of about 4,065,576 (293)

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Frequency of Low Bone Mineral Density (BMD) in Patients with Liver Cirrhosis

Journal of Pharmaceutical Research International, 2021
Objective: The objective of this study was to evaluate the low bone mineral density (BMD) in patients with liver cirrhosis. Methodology: This cross sectional study on 151 Liver cirrhotic patients was conducted at Liaquat University Hospital Hyderabad/Jamshoro. This study duration was 6 months, July 2015 to December 2015.
Muhammad Akram Bajwa, Kapeel Raja, Prem Kumar, Narindar Kumar, Nasrullah Aamer, Ihsanullah Rajar   +5 more
openaire   +2 more sources

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Seeing Through the Density: A Case of Misleading BMD Results on bone densitometry

Journal of the Pakistan Medical Association
Bone mineral densitometry (BMD) using dual-energy X-ray absorptiometry (DXA) is widely recognized as the standard method for evaluating bone density. DXA produces attenuation maps that aid in measuring BMD. Non-relevant findings are commonly observed in
Syeda Hadia Najam, Aamna Hassan
doaj   +1 more source

Bone mineral density evaluation o epileptic children on anti-epileptic medications

The Egyptian Journal of Radiology and Nuclear Medicine, 2017
Objective: The aim of this work is to evaluate bone mineral density (BMD) in children with idiopathic epilepsy under anti-epileptic drugs and to determine the effect of the type and the duration of drug administration on BMD.
Nasr Mohamed M. Osman, Reem A. Abdel Aziz, Gamal T. Soliman, Asmaa Gamal Mohamed   +3 more
doaj   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Association of total testosterone status with bone mineral density in adults aged 40–60 years

Journal of Orthopaedic Surgery and Research, 2021
Objective Evidence linking total testosterone and bone mineral density (BMD) in adults is very limited. According to our review of the literature, only a few reports have focused on the relationship between total testosterone and bone mineral density in ...
Nan Wang, Lixiang Wang, Chengcheng Huang
doaj   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Comparison of Bone Mineral Density of Dominant and Non-dominant Forearm of Badminton Players

Türk Spor ve Egzersiz Dergisi, 2019
Research related to arm bone density of badminton players focused mainly on humerus, how much forearm exposed to physical load is affected by this stress has been studies less.
Mustafa Şakir Akgül, Arzu Altunel, Veli Volkan Gürses, Bilgehan Baydil   +3 more
doaj   +1 more source

Perimenopausal Bone Loss Is Associated with Ovulatory Activity—Results of the PeKnO Study (Perimenopausal Bone Density and Ovulation)

Diagnostics, 2022
Background: During the menopausal transition, around 25% of women experience a particularly accelerated loss of bone mineral density. These so-called “fast bone losers” represent a group of patients with an increased risk of osteoporosis.
Teresa Starrach, Anita Santl, Vanadin Regina Seifert-Klauss   +2 more
doaj   +1 more source