Results 71 to 80 of about 4,065,576 (293)

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Advanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He   +10 more
wiley   +1 more source

AB0188 Bone mineral density(bmd), serum calcidiol and knee osteoarthritis [PDF]

Annals of the Rheumatic Diseases, 2001
Background Relationship between knee osteoarthritis (OA) and bone mass has brought a great interest. Serum calcidiol (CS) low level has been associated with a higher incidence and faster progression of OA in elderly women, but this relation has not been defined in young postmenopausal women.
M Bonilla Hernán, P Aguado, L Vacchiano, E Martinez, F Gamero, B Berriatua, E Martín Mola   +6 more
openaire   +1 more source

Clinical factors associated with trabecular bone score.

, 2013
Dual-energy X-ray absorptiometry (DXA) measurement of bone mineral density (BMD) is the reference standard for diagnosing osteoporosis but does not directly reflect deterioration in bone microarchitecture.
Hans, D., Leslie, W.D., Manitoba Bone Density, Program, Krieg, M.A., Hans D, Krieg MA, Leslie WD   +6 more
core   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Association between Body Mass Index and Bone Mineral Density in Patients Referred for Dual-Energy X-Ray Absorptiometry Scan in Ajman, UAE

Journal of Osteoporosis, 2011
Body Mass Index (BMI) is a good indicator for measurements of Bone Mineral Density (BMD) which measures the density of minerals present in the bones using a special scan.
Tarek Fawzy, Jayakumary Muttappallymyalil, Jayadevan Sreedharan, Amal Ahmed, Salma Obaid Saeed Alshamsi, Mariyam Saif Salim Humaid Bin Bader Al Ali, Khawla Ahmed Al Balsooshi   +6 more
doaj   +1 more source

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

Advanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing, Lanxin Gu, Lipeng Fu, Xin Gao, Zechuan Li, Hui Zhang, Wenpeng Song, Huixin Lv, Yongsheng Zhou, Ping Zhang   +9 more
wiley   +1 more source

The global, regional, and national burden attributable to low bone mineral density, 1990–2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021

BACKGROUND: Fractures related to osteoporosis and low bone mineral density lead to substantial morbidity, mortality, and cost to individuals and health systems.
GBD 2021 Low Bone Mineral Density Collaborators
core   +1 more source

Forest plot with odds ratio (MD) of bone mineral density (BMD) in subgroup of HSPC.

, 2022
Forest plot with odds ratio (MD) of bone mineral density (BMD) in subgroup of HSPC.
Mandi Lin (13844322), Xinxiang Fan (467985), Songtao Xiang (5949191), Weiting Qin (467615), Chiwei Chen (13844319), Renlun Huang (7871009), Daocheng Yu (13844325), Jianfu Zhou (13844328), Lang Guo (9276449)   +8 more
core   +1 more source

Spatiotemporally Precise Rheumatoid Arthritis Therapy via a Triple‐Locked Cascaded Nanoplatform With Dual‐Channel Self‐Reporting

Advanced Science, EarlyView.
An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu, Wendi Zhu, Shiyun Xu, Shichang Liu, Wenjun Tang, Xiaoyu Ma, Ting Yang, Haojian Yang, Hongtong Wang, Lu Cao, Lijie Tan, Qi Wang   +11 more
wiley   +1 more source

Determination of baseline bone mineral density using dual energy X-ray absorptiometry in Suffolk-Dorset hybrid ewes

International Journal of Veterinary Science and Medicine, 2017
Dual energy x-ray absorptiometry (DEXA) has the ability to rapidly and non-invasively measure bone mineral density and is the most widely accepted method for quantitative assessment of bone mineral status in vivo. There is scarce information available on
Subburamanujam Ayyappan, Bharathi Niveditha, Gert J. Breur   +2 more
doaj   +1 more source