Results 81 to 90 of about 53,845 (250)

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source

Metabolomics-based profiles predictive of low bone mass in menopausal women

Bone Reports, 2018
Osteoporosis is a skeletal disorder characterized by compromised bone strength and increased risk of fracture. Low bone mass and/or pre-existing bone fragility fractures serve as diagnostic criteria in deciding when to start medication for osteoporosis ...
Takeshi Miyamoto, Akiyoshi Hirayama, Yuiko Sato, Tami Koboyashi, Eri Katsuyama, Hiroya Kanagawa, Atsuhiro Fujie, Mayu Morita, Ryuichi Watanabe, Toshimi Tando, Kana Miyamoto, Takashi Tsuji, Atsushi Funayama, Tomoyoshi Soga, Masaru Tomita, Masaya Nakamura, Morio Matsumoto   +16 more
doaj   +1 more source

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a serious illness in which more than half of all deaths are due to malnutrition. Critically low energy and protein intake are known causes of massive weight loss, whereas micronutrient deficiencies due to a low‐calorie food pattern remain poorly characterized in children with AN. Micronutrient deficiencies in
Zenaida Iordan, Diane Morfin, Marion Bernetiere, Marie Fauchet, Noël Peretti, Bérénice Segrestin, Pierre Poinsot   +6 more
wiley   +1 more source

THE AGE-RELATED FEATURES OF ALVEOLAR JAWS BONE MINERAL DENSITY IN GROWING CHILDREN

Український стоматологічний альманах, 2018
Introduction. Mechanical and biological properties of jaw bone regards in the planning, effectiveness and prognosis of dental treatment. It’s quantitative and qualitative parameters are factors which influence on the dental implantation reconstructive ...
V.F. Makeev, A-S.A. Krupnyk
doaj  

Assessing Clinical Severity and Prognosis in Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa Using the Albumin‐Globulin Ratio

European Eating Disorders Review, EarlyView.
ABSTRACT Objective The albumin‐globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).
Eylem Şerife Kalkan, Ayşe Bilge Baklaci, Yelda Kiliç, Sinem Akgül, Nilgün Özgül, Melis Pehlivanturk Kizilkan   +5 more
wiley   +1 more source

Matching TGF‐β1 Activation With Stress‐Responsive Charge‐Reversal Hydrogel Microspheres for the Treatment of Osteoarthritis

Exploration, EarlyView.
Based on the interaction between the weakly cross‐linked disulfide bonds that break under stress and charge‐reversal messenger molecules, we herein achieved nanoparticle charge reversal under stress and constructed a stress‐responsive charge‐reversal hydrogel microsphere system using microfluidic technology.
Feng Lin, Yiwen Xu, Lei Xiang, Yueliang Zhu, Yihan Li, Yaping Zhuang, Zengjie Zhang, Jiayu Chen, Heemin Kang, Ning Zhang, Xiaohua Yu, Wenguo Cui   +11 more
wiley   +1 more source

Femoral Skeletal Growth in Early Infancy Assessed by Radiofrequency Echographic Multi‐Spectrometry

Journal of Clinical Ultrasound, EarlyView.
Radiofrequency echographic multi‐spectrometry (REMS) acquisition of raw ultrasound radiofrequency signals from neonatal bone. Signals undergo preprocessing and frequency‐domain analysis to extract spectral features reflecting bone properties. A software‐guided procedure then identifies and selects standardized regions of interest (ROIs).
Serafina Perrone, Virginia Beretta, Laura Cannavò, Domenico Corica, Tommaso Aversa, Giorgia Pepe, Letteria Morabito, Maria Elisabeth Street, Malgorzata Wasniewska, Tullio Ghi, Andrea Dall'Asta   +10 more
wiley   +1 more source

Characteristics of Bone Turnover in the Long Bone Metaphysis Fractured Patients with Normal or Low Bone Mineral Density (BMD)

PLoS ONE, 2014
The incidence of osteoporotic fractures increases as our population ages. Until now, the exact biochemical processes that occur during the healing of metaphyseal fractures remain unclear. Diagnostic instruments that allow a dynamic insight into the fracture healing process are as yet unavailable.
Christoph Wölfl, Daniela Schweppenhäuser, Thorsten Gühring, Caner Takur, Bernd Höner, Ulrich Kneser, Paul Alfred Grützner, Leila Kolios   +7 more
openaire   +4 more sources

Shared foraging behaviors between hyenas and hominins in the Middle Paleolithic Levant: New evidence from Geula Cave, Israel

Journal of Quaternary Science, EarlyView.
ABSTRACT While competition with large carnivores is likely to have shaped Middle Paleolithic hominins' subsistence behavior, palimpsested human and carnivore accumulations render the signal challenging to isolate. This study presents a detailed zooarchaeological and taphonomic analysis of a non‐anthropogenic faunal assemblage from a MIS 5 (~130–80 ka ...
Meir Orbach, Omry Barzilai, Israel Hershkovitz, Ma'ayan Lev, Reuven Yeshurun   +4 more
wiley   +1 more source

Combinations of two imaging parameters to improve bone mineral density (BMD) assessment in patients with lumbar degenerative diseases. [PDF]

BMC Musculoskelet Disord, 2023
Li W, Zhu H, Tian H, Tong T, Hua Z, Zhao X, Shen Y, Wang L.   +7 more
europepmc   +1 more source