CellsPrevious reports have described a statistical association between high-density lipoproteins (HDL) subclasses and the expression of genes coding for pro-calcifying proteins in the epicardial adipose tissue of patients with coronary artery disease (CAD ...
María Luna-Luna +12 more
doaj +1 more source
Biogran Grafting in Rat Tibia Defects - A Model of High Bone Metabolism Site [PDF]
Brazilian Archives of Biology and TechnologyWe investigated the Biogran on bone repair and metabolism at several time-intervals upon grafting into rat tibia artificial defects. The biomaterial was thoroughly characterized in vitro, and its dissolution behavior upon immersion was assessed in ...
Luiza de Almeida Queiroz Ferreira +12 more
doaj +1 more source
Chitosan scaffolds containing calcium phosphate salts and rhBMP-2: in vitro and in vivo testing for bone tissue regeneration. [PDF]
PLoS ONE, 2014 Numerous strategies that are currently used to regenerate bone depend on employing biocompatible materials exhibiting a scaffold structure. These scaffolds can be manufactured containing particular active compounds, such as hydroxyapatite precursors and ...
Rodrigo Guzmán +7 more
doaj +1 more source
Experimental Spinal Fusion With Recombinant Human Bone Morphogenetic Protein-2 Without Decortication of Osseous Elements [PDF]
, 1997 Study Design. L4-L5 intertransverse process fusions were produced with 58 μg, 230 μg, or 920 μg of recombinant human bone morphogenetic protein-2 in 20 dogs. Eleven had traditional decortication of posterior elements before insertion of the implant. Nine
Dawson, Edgar G. +6 more
core +1 more source
BMP2/BMPR1A is linked to tumour progression in dedifferentiated liposarcomas [PDF]
, 2016 Bone Morphogenic Protein 2 (BMP2) is a multipurpose cytokine, important in the development of bone and cartilage, and with a role in tumour initiation and progression.
Cassidy, A.P. +3 more
core +3 more sources
The role of skeletal tissue remodeling markers in the patho-genesis of implant-associated inflammation after primary knee arthroplasty [PDF]
Саратовский научно-медицинский журнал, 2018 Aim: to reveal certain mechanisms of the pathogenesis of implant-associated inflammation by the level of resorption and bone tissue genesis markers in patients who underwent primary knee arthroplasty. Material and Methods.
Galashina Е.А. +3 more
doaj
Accelerators of Osteogenesis by Recombinant Human Bone Morphogenetic Protein-2
Drug Target Insights, 2007 Bone morphogenetic protein (BMP) appears to be one of the most promising cytokine and for clinical use in reconstructive surgery for bony defects and augmentation.
Yasunori Okubo +2 more
doaj +2 more sources
Noggin depletion in adipocytes promotes obesity in mice. [PDF]
, 2019 ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M +14 more
core +1 more source
Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]
, 2014 The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam +5 more
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Expression, purification and in vitro biological activity from human recombinant BMP-2 produced by a novel approach [PDF]
, 2006 Bone morphogenetic proteins have promoted great biomedical interest due to their ability in inducing new bone formation when used as powerful osteoinductive components of several late-stage bone grafting products.
Bessa, Paulo C. +6 more
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