Results 71 to 80 of about 21,412 (315)

Patient-Specific Finite-Element Analysis of Three Intramedullary Nails for Tibiotalocalcaneal Fusion

open access: yesFoot & Ankle Orthopaedics, 2017
Category: Ankle, Hindfoot Introduction/Purpose: Tibiotalocalcaneal (TTC) arthrodesis is a salvage procedure for patients with severe osteoarthritis and other degenerative ankle conditions.
Christopher Yakacki PhD   +3 more
doaj   +1 more source

Expandable intramedullary nail: review of biomechanical studies

open access: yesRussian Open Medical Journal, 2016
This article reviews studies of Fixion expandable nail biomechanical properties in case of long bones fractures osteosynthesis. The purpose of this study was to systematize biomechanical researches dedicated to the expandable nail. There were found seven
Dmitry Ivanov   +2 more
doaj   +1 more source

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

open access: yesAdvanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang   +7 more
wiley   +1 more source

Bioprinting of Microtissues Within Mechanically Tunable Support Baths to Engineer Anisotropic Musculoskeletal Tissues

open access: yesAdvanced Science, EarlyView.
This study presents a novel 4D bioprinting platform for engineering biomimetic musculoskeletal grafts. By tuning the mechanical properties of support baths, we enhance tissue fusion, collagen alignment, and cell differentiation. Using this strategy, we successfully fabricate scaled‐up, anisotropic tissues such as meniscus, articular cartilage, and ...
Francesca D. Spagnuolo   +2 more
wiley   +1 more source

Review on lower limb bone fracture fixation: biomechanics, design, and advancements in additive manufacturing for implants

open access: yesMaterials & Design
Bone fractures in the lower limbs, pose significant challenges in orthopaedic treatment due to the need for effective stabilization and healing. To contextualize recent advances, data indicate that lower limb fractures account for 20.2 % of all fractures.
Ali Mehboob   +2 more
doaj   +1 more source

Intramedullary Nailing for Paediatric Diaphyseal Forearm Bone Fracture

open access: yesKathmandu University Medical Journal, 2012
Background Though most of the pediatric diaphyseal forearm bone fracture can be treated with closed reduction and cast application, indications for operative intervention in pediatric both-bone forearm fractures include open fractures, irreducible fractures, and unstable fractures.
N P, Parajuli   +5 more
openaire   +3 more sources

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

open access: yesAdvanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang   +7 more
wiley   +1 more source

Using Three-Dimensional Computational Modeling to Compare the Geometrical Fitness of Two Kinds of Proximal Femoral Intramedullary Nail for Chinese Femur

open access: yesThe Scientific World Journal, 2013
Objective. The aim of this study was to use three-dimensional (3D) computational modeling to compare the geometric fitness of these two kinds of proximal femoral intramedullary nails in the Chinese femurs. Computed tomography (CT) scans of a total of 120
Sheng Zhang   +5 more
doaj   +1 more source

Closed intramedullary nailing in forearm bone fractures without use of intraoperative imaging [PDF]

open access: diamond, 2018
Manish R Shah   +5 more
openalex   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan   +13 more
wiley   +1 more source

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