Results 91 to 100 of about 2,891,223 (328)

Carbon-fiber reinforced intramedullary nailing in musculoskeletal tumor surgery: a national multicentric experience of the Italian Orthopaedic Society (SIOT) Bone Metastasis Study Group.

open access: yesInjury, 2017
INTRODUCTION Carbon fiber reinforced (CFR) implants have been proposed for the treatment of fractures or impending fractures of the long bones in the oncology patient.
A. Piccioli   +13 more
semanticscholar   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

open access: yesAdvanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng   +19 more
wiley   +1 more source

A Novel Dynamic Compression Angle-Stable Interlocking Intramedullary Nail: Description, Validation, and Model Evaluation

open access: yesVeterinary Medicine International
The stabilization of long-bone fractures using intramedullary nails offers significant biological advantages for bone healing. Nevertheless, the mechanical stability of the implant–bone interface remains suboptimal due to the absence of models capable of
Luís Gustavo Gosuen Gonçalves Dias   +4 more
doaj   +1 more source

Static Study and Finite Element Analysis of a New Method of Fixation of a Medial Humerus Fracture by an Intramedullary Nailing System Analyzed by the ANSYS Workbench 16.2 Calculus Code

open access: yesNano Biomedicine and Engineering, 2019
Comminuted fractures of the humerus are generally treated with the intramedullary rod fixed by screws or locking plate system, and clinical results are satisfactory. We also know very well that the success of this agriculture depends on the stability and
Brahim Keddar   +5 more
doaj   +1 more source

Open Intramedullary Nailing for Segmental Long Bone Fractures: An Effective Alternative in a Resource-restricted Environment

open access: yesNigerian Journal of Surgery, 2016
Background: Closed, locked intramedullary nailing has been accepted as the gold standard in the care of femoral fractures, with reported union rates as high as 98-100%.
O. Babalola   +5 more
semanticscholar   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

open access: yesAdvanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang   +7 more
wiley   +1 more source

Predictive value of tip apex distance and calcar-referenced tip apex distance for cut-out risk in intertrochanteric femur fractures treated with double lag screw proximal femoral nails

open access: yesActa Orthopaedica et Traumatologica Turcica
Objective: Cut-out is a major mechanical complication following proximal femoral nailing for intertrochanteric femur fractures. Tip apex distance (TAD) and calcar-referenced TAD (CalTAD) are key radiographic parameters used to predict this complication.
Mehmet Akan, Dıhye Sezen, Hayati Kart
doaj   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

open access: yesAdvanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang   +19 more
wiley   +1 more source

Extendable intramedullary nailing in a child with osteogenesis imperfecta of bilateral femoral fractures: a case report

open access: yesFrontiers in Surgery
BackgroundOsteogenesis imperfecta, commonly referred to as brittle bone disease, is the most prevalent monogenic bone disorder and is characterized by osteoporosis and heightened bone fragility.
Weishuai Zhang   +4 more
doaj   +1 more source

Results of surgical management in patients with metastasis to the hip

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated surgical methods and results in patients who were treated by various internal fixation and arthroplastic methods for impending or pathological fractures around the hip joint due to symptomatic bone metastasis.\nMethods: The study
Levent Eralp   +3 more
doaj  

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