Results 91 to 100 of about 1,012,906 (291)

Open reduction and intramedullary fixation through minimal incision with Ender nails in femoral fractures of children aged from 6 to 16 years

Acta Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated functional and radiologic results of the treatment in patients aged 6 to 16 years, who underwent indirect reduction with Ender nails through minimal incisions for troublesome femoral fractures.\nMethods: We treated femoral ...
Onder Kalenderer, Haluk Agus, Coskun Sanli   +2 more
doaj  

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Results of surgical management in patients with metastasis to the hip

Acta Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated surgical methods and results in patients who were treated by various internal fixation and arthroplastic methods for impending or pathological fractures around the hip joint due to symptomatic bone metastasis.\nMethods: The study
Levent Eralp, Harzem Ozger, Adnan Karaoglu, Eray Bozan   +3 more
doaj  

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Bone Lengthening in Short Stature Using Motorized Nails

Journal of Limb Lengthening & Reconstruction
Context: Motorized intramedullary nails are the gold standard for bone lengthening, yet few studies have evaluated their impact on quality of life. Aims: This study assessed the influence of motorized intramedullary lower limb lengthening in patients ...
Amandine Eon, Tristan Langlais, Jerôme Sales De Gauzy, Franck Accadbled   +3 more
doaj   +1 more source

Intramedullary Flexible Nailing for Diaphyseal Fractures of Forearm Bones in Children [PDF]

Revista Brasileira de Ortopedia
Objectives Most of the fractures of the bones of the forearm in children are successfully treated conservatively with closed reduction and casting. The outcomes remain variable and the patients may require additional fracture manipulation or formal ...
Balakrishnan M. Acharya, Pramod Devkota, Abhishek K. Thakur, Bidur Gyawali   +3 more
doaj   +3 more sources

Beyond the Skin: Nail Clues to a Bone Disease

Cureus
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory bone disorder that predominantly affects children, and approximately 25% patients also present with an associated inflammatory condition. Most patients respond to nonsteroidal anti-inflammatory drugs, but refractory cases may need corticosteroids, bisphosphonate therapy, or ...
Costa, Mariana, Tavares, Catarina, Alves, Cristina, Coelho, Paulo, Nascimento, João   +4 more
openaire   +3 more sources

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Biointegrative fiber-reinforced implants for fixation of subchondral insufficiency with avascular necrosis: a case report

Journal of Cartilage & Joint Preservation
Introduction: Treating avascular necrosis (AVN) of the knee can be challenging, particularly at later stages of progression. After subchondral collapse occurs, the only existing surgical treatment is arthroplasty.
Sarah A. Muth, Alexander C. Weissman, Allen A. Yazdi, Katie J. McMorrow, Richard M. Danilkowicz, Brian J. Cole   +5 more
doaj   +1 more source

Plate-assisted Bone Segment Transport With Motorized Lengthening Nails and Locking Plates:A Technique to Treat Femoral and Tibial Bone Defects [PDF]

, 2019
This article describes a new bone transport technique for femoral and tibial bone defects using lengthening nails combined with locking plates. We term it plate-assisted bone segment transport (PABST).Methods: Nine patients with five femoral and four ...
Green, Connor J, Prince, Daniel E, McNally, Martin A, Singh, Upender Martin, Gardner, Matthew P, Olesen, Ulrik Kähler, Herzenberg, John E, Nygaard, Tobias   +7 more
core   +1 more source