Results 81 to 90 of about 21,705 (315)

Intraosseous High Dose Rate Brachytherapy (HDR) with Intramedullary Nailing for Long Bone Metastases – A Feasibility Study [PDF]

open access: bronze, 2020
Bhavani S. Gannavarapu   +6 more
openalex   +1 more source

INTERLOCKED INTRAMEDULLARY NAILING OF LONG BONES

open access: yesThe Professional Medical Journal, 2008
.. Intramedullary interlocking nailing is the recommended procedure of fixation of long bones fracture. This type of fixation allowthe patient to walk independently in few days time, but unlikely there are only few centers in our country which are doing this practice. InMansoor Orthopedic Hospital and Sandeman Civil Hospital Quetta we started this type
MANSOOR ILYAS   +2 more
openaire   +2 more sources

Thromboembolism After Intramedullary Nailing for Metastatic Bone Lesions

open access: yesJournal of Bone and Joint Surgery, 2015
The risk of venous thromboembolism (VTE) in patients undergoing intramedullary nailing for skeletal metastatic disease is currently undefined. The purpose of our study was to determine the risk of thromboembolic events, to define the risk factors for VTE, and to define the rate of wound complications in this population.A retrospective review of ...
Shallop, Brandon   +8 more
openaire   +3 more sources

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

open access: yesAdvanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen   +15 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Biointegrative fiber-reinforced implants for fixation of subchondral insufficiency with avascular necrosis: a case report

open access: yesJournal of Cartilage & Joint Preservation
Introduction: Treating avascular necrosis (AVN) of the knee can be challenging, particularly at later stages of progression. After subchondral collapse occurs, the only existing surgical treatment is arthroplasty.
Sarah A. Muth   +5 more
doaj   +1 more source

Patient-Specific Finite-Element Analysis of Three Intramedullary Nails for Tibiotalocalcaneal Fusion

open access: yesFoot & Ankle Orthopaedics, 2017
Category: Ankle, Hindfoot Introduction/Purpose: Tibiotalocalcaneal (TTC) arthrodesis is a salvage procedure for patients with severe osteoarthritis and other degenerative ankle conditions.
Christopher Yakacki PhD   +3 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

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