Results 81 to 90 of about 1,012,906 (291)

Intramedullary Nailing of Both Bone Forearm Fractures in Children by Rush Nails and Titanium Elastic Nails

Journal of Universal College of Medical Sciences, 2018
INTRODUCTION: Forearm fractures are common upper limb injuries among children and usually treated nonoperatively. Failure of nonoperative treatment, open injuries and multiple fractures are the indications for surgery in paediatric both bone forearm fractures.
Som Ale, Rahul Shrestha, Sagar Panthi, Subin Byanjankar, Ruban Joshi, Rajeev Dwivedi   +5 more
openaire   +2 more sources

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Extendable intramedullary nailing in a child with osteogenesis imperfecta of bilateral femoral fractures: a case report

Frontiers in Surgery
BackgroundOsteogenesis imperfecta, commonly referred to as brittle bone disease, is the most prevalent monogenic bone disorder and is characterized by osteoporosis and heightened bone fragility.
Weishuai Zhang, Xuchao Lu, Nannan Yang, Xianyou Zhu, Haotian Hu   +4 more
doaj   +1 more source

Management of unicameral bone cysts by intramedullary flexible nails: a series of 18 children [PDF]

The Egyptian Orthopaedic Journal
IntroductionThe intracystic injection of methylprednisolone acetate, curettage with bone grafting, osteoinductive treatments employing demineralized bone matrix, and intramedullary fixation with flexible nails are being used to treat unicameral bone ...
Vivek Sodhai, Chaitrali Gundawar, Sandeep Patwardhan, Arjun K Unnam, Parag Sancheti   +4 more
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Review on lower limb bone fracture fixation: biomechanics, design, and advancements in additive manufacturing for implants

Materials & Design
Bone fractures in the lower limbs, pose significant challenges in orthopaedic treatment due to the need for effective stabilization and healing. To contextualize recent advances, data indicate that lower limb fractures account for 20.2 % of all fractures.
Ali Mehboob, Imad Barsoum, Rashid K. Abu Al-Rub   +2 more
doaj   +1 more source

Longterm functional results of adult intraarticular distal humeral fractures treated by open reduction and plate osteosynthesis

Acta Orthopaedica et Traumatologica Turcica, 2021
Objectives: We assessed the long-term functional results of surgical treatment of distal intra-articular humeral fractures, together with the factors having influence on the outcome.\nMethods: Thirty-four patients (25 males, 9 females; mean age 38 years;
Mustafa Urguden, Yetkin Soyuncu, Tevfik Aslan   +2 more
doaj  

Clinical outcomes following treatment of extracapsular hip fractures with long compared with short cephalomedullary nails. [PDF]

AIMS: The use of cephalomedullary nails for the fixation of extracapsular hip fractures has increased in recent years, but high-quality evidence to guide surgical decision-making between long and short cephalomedullary nails is lacking.
Peach, C, Wood, R, Heaton, S, Sharma, A, Appelbe, D, Bhaskar, D, Charalambous, CP, Blocker, O, Faisal, M, Dasari, K, Bigsby, E, Middleton, R, Elgalli, M, Berstock, J, Page, P, Dunlop, D, Moppett, I, Davison, J, Maqsood, M, Bird, J, McAndrew, A, Ellapparadja, P, Barrett, M, Acharya, M, Ng, A, Farrar, M, Yarlagadda, R, Eardley, W, Reed, M, Johnson, D, Gallagher, K, Diamond, O, Malek, I, Rajagopalan, S, Mohanty, K, Cook, JA, Gee, M, Sheeraz, A, Gill, I, Slater, G, Sloan, A, Srinivasan, S, Jimenez, A, Hull, P, Sturridge, S, Bhatnagar, S, Ollivere, B, Kosy, J, Melling, D, Dunbar, M, McClelland, D, Achten, J, Kozdryk, J, Bajada, S, Handley, R, McNamara, I, Rogers, B, Smith, G, Dixon, P, Hutchinson, D, Dhinsa, B, Longstaff, L, Young, J, Magill, P, Sorial, A, Vashista, G, Joachim, T, Ghande, A, Goh, EL, Kulkarni, A, Kelly, A, Fearon, P, Png, ME, Metcalfe, D, Costa, ML, Clark, C, Theivendran, K, Craik, J, Savaridas, T, Mahmood, A, Chesser, T, Sree, D, Butler, OK, WHiTE Investigators, Penny, J, Griffin, XL, Remedios, ID   +86 more
core   +1 more source

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

Advanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao, Jinpei Sun, Chenxi Zhao, Yuting Cang, Keyu Zong, Yuxin Guo, Yajing Wang, Di Meng, Qingling Song, Lei Wang   +9 more
wiley   +1 more source

Biomechanical design considerations of a 3D-printed tibiotalocalcaneal nail for ankle joint fusion

3D Printing in Medicine
Tibiotalocalcaneal (TTC) arthrodesis treatment using intramedullary nails faces significant challenges due to inadequate bone integration and mechanical stability.
Kin Weng Wong, Shao-Fu Huang, Skye Hsin-Hsien Yeh, Tai-Hua Yang, Cheng-Yi Liang, Chun-Li Lin   +5 more
doaj   +1 more source