Results 101 to 110 of about 2,650,892 (412)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Serum MicroRNA signatures associated with hypertrophic callus formation in polytrauma patients with traumatic brain injury

Scientific Reports
Long-bone fractures occasionally develop excessive callus formation in the presence of traumatic brain injury, a clinically relevant but poorly understood injury response.
Thomas Lettner, Florian Dussing, Renate Gehwolf, Christian Deininger, Amelie Deluca, Verena Wally, Valeska Hofmann, Matthias Hackl, Andreas Traweger, Florian Wichlas   +9 more
doaj   +1 more source

Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone

Journal of Orthopaedic Translation, 2020
Summary: Background: Abnormal bone formation in subchondral bone resulting from uncoupled bone remodeling is considered a central feature in osteoarthritis (OA) pathogenesis. H-type vessels can couple angiogenesis and osteogenesis.
Yanjun Hu, Hangtian Wu, Ting Xu, Yutian Wang, Hanjun Qin, Zilong Yao, Peisheng Chen, Yongheng Xie, Zhiguo Ji, Kaifan Yang, Yu Chai, Xianrong Zhang, Bin Yu, Zhuang Cui   +13 more
doaj   +1 more source

Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells. [PDF]

, 2015
Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity.
Beegle, Julie R, Chávez, Myra N, Egaña, José T, Fierro, Fernando A, Isseroff, Roslyn R, O'Neal, Adam J, Peavy, Thomas R   +6 more
core   +2 more sources

Improving Bone Formation by Guided Bone Regeneration Using a Collagen Membrane with rhBMP-2: A Novel Concept [PDF]

, 2023
Narae Jung, Jaehan Park, Sang Hyun Park, Seunghan Oh, Sungtae Kim, Sung Won Cho, Jong‐Eun Kim, Hong‐Seok Moon, Young‐Bum Park   +8 more
openalex   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu‐Jing Li   +8 more
wiley   +1 more source

Bone regeneration and stem cells [PDF]

Journal of Cellular and Molecular Medicine, 2011
This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair ...
Arvidson K., Abdallah B. M., Applegate L. A., BALDINI, NICOLA, Cenni E., Gomez Barrena E., Granchi D., Kassem M. F., Konttinen Y. T., Mustafa K., Pioletti D. P., Sillat T., Finne Wistrand A.   +12 more
openaire   +5 more sources

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Effect of Polycaprolactone Scaffold Permeability on Bone Regeneration In Vivo [PDF]

, 2011
Successful bone tissue engineering depends on the scaffold's ability to allow nutrient diffusion to and waste removal from the regeneration site, as well as provide an appropriate mechanical environment.
Harris, Matthew T., Hollister, Scott J., Kemppainen, Jessica Marie, Mitsak, Anna G.   +3 more
core   +2 more sources

Biomaterials for bone regeneration: an orthopedic and dentistry overview

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2021
Because bone-associated diseases are increasing, a variety of tissue engineering approaches with bone regeneration purposes have been proposed over the last years.
J. Girón, E. Kerstner, T. Medeiros, L. Oliveira, G. M. Machado, C. Malfatti, P. Pranke   +6 more
semanticscholar   +1 more source