Results 101 to 110 of about 174,184 (273)

DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes

Scientific Reports, 2017
The Runt-related transcription factor 2 (RUNX2) is critical for bone formation as well as chondrocyte maturation. Matrix metalloproteinase (MMP)-13 is a major contributor to cartilage degradation in osteoarthritis (OA).
Atsushi Takahashi, María C. de Andrés, Ko Hashimoto, Eiji Itoi, Miguel Otero, Mary B. Goldring, Richard O. C. Oreffo   +6 more
doaj   +1 more source

Persistent presence of common ALL-antigen (cALLa)-positive cells in regenerating bone marrow after cessation of maintenance therapy in ALL of childhood [PDF]

, 1985
J. A. J. M. Bakkeren, Gam de Vaan
openalex   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

T-cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived versus thymic-independent progeny [PDF]

, 1993
CL Mackall, L Granger, Sheard Ma, Rosemarie Cepeda, RE Gress   +4 more
openalex   +1 more source

Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting

Advanced Healthcare Materials, EarlyView.
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen, James Davies, Aditya Ashok, Trung Thien Hoang, Anahid Ehteda, Tran Bach Dang, Emanuele Nicotra, Hien A. Tran, Bibhu Sharma, Kefan Zhu, Phuoc Thien Phan, Adrienne Ji, Jingjing Wan, Jelena Rnjak‐Kovacina, Orazio Vittorio, Hoang‐Phuong Phan, Nigel Hamilton Lovell, Thanh Nho Do   +17 more
wiley   +1 more source

Large-sized bone defect repair by combining a decalcified bone matrix framework and bone regeneration units based on photo-crosslinkable osteogenic microgels

Bioactive Materials, 2022
Physiological repair of large-sized bone defects is great challenging in clinic due to a lack of ideal grafts suitable for bone regeneration. Decalcified bone matrix (DBM) is considered as an ideal bone regeneration scaffold, but low cell seeding ...
Junxiang Hao, Baoshuai Bai, Zheng Ci, Jincheng Tang, Guanhuai Hu, Chengxiang Dai, Mengyuan Yu, Meng Li, Wei Zhang, Yixin Zhang, Wenjie Ren, Yujie Hua, Guangdong Zhou   +12 more
doaj  

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

Advanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong, Wenao Liao, Lingcong Xu, Niezhenghao He, Ke Xu, Caiyuan Liu, Fei Wang, Wei Zhang, Jiang Hu, Haowen Cui   +9 more
wiley   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

The L-shaped association between body roundness index and all-cause mortality in osteoporotic patients: a cohort study based on NHANES data

Frontiers in Nutrition
PurposeThis study aims to investigate the relationship between the body roundness index (BRI) and overall mortality rates in individuals with osteoporosis (OP), utilizing information sourced from the NHANES database, in order to assess BRI’s capability ...
Ziyao Ding, Ziyao Ding, Ziyao Ding, Wenbo Li, Wenbo Li, Wenbo Li, Haixu Qi, Haixu Qi, Haixu Qi, Tianci Fang, Qirui Zhu, Qirui Zhu, Qirui Zhu, Xinzhe Qu, Xinzhe Qu, Changchang Chen, Jun Sun, Jun Sun, Yong Pang   +18 more
doaj   +1 more source

Membrane-guided bone regeneration: Segmental radius defects studied in the rabbit [PDF]

, 1995
Rickard Nyman, Marteinn Magnusson, Lars Sennerby, Sture Nyman, Dan Lundgren   +4 more
openalex   +1 more source