Results 81 to 90 of about 4,056,235 (345)

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

Advanced Science
Tendinopathy is a long‐lasting, debilitating disease that not only affects patients' individual lives, but also imposes a significant socioeconomic burden.
Renate Gehwolf, Herbert Tempfer, Nevra Pelin Cesur, Andrea Wagner, Andreas Traweger, Christine Lehner   +5 more
doaj   +1 more source

Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

Nature Communications, 2020
Nanoclays have been used in composites and for drug delivery but have suffered from a trade-off in properties when used for both. Here the authors report on the use of bisphosphonate interactions with nanoclay edges to made drug loaded composites without
Yang-Hee Kim, Xia Yang, Liyang Shi, Stuart A. Lanham, Jons Hilborn, Richard O. C. Oreffo, Dmitri Ossipov, Jonathan I. Dawson   +7 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Comparative Evaluation of Ultrasonic and Sonic Irrigant Activation Systems: Assessing Extrusion Risk, Debridement, and Biofilm Removal in Distinct Apical Preparation Sizes

Applied Sciences
This study aims to compare the effectiveness of ultrasonically and sonically activated irrigation in terms of extrusion risk, root canal debridement, and biofilm removal, considering distinct apical preparation sizes, through an ex vivo study in human ...
Sara Paixão, Pedro Sousa Gomes, Maria Helena Fernandes, Cláudia Rodrigues, Liliana Grenho   +4 more
doaj   +1 more source

Glandular Odontogenic Cyst in the Anterior Mandible: A Case Report of a Conservative Approach and a Recurrence Detection

Diagnostics, 2023
Purpose: The glandular odontogenic cyst (GOC) is considered a rare developmental cyst, with an odontogenic origin and both epithelial and glandular characteristics, with less than 200 reported cases in the literature.
Wladimir Gushiken de Campos, Rita Araújo, Victor Martin, Marília Trierveiler, Pedro Gomes, Celso Augusto Lemos   +5 more
doaj   +1 more source

Strategies for Bone Regeneration: From Graft to Tissue Engineering

International Journal of Molecular Sciences, 2021
Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very dynamic tissue subjected to continuous remodeling in order to preserve its structure and function.
G. Battafarano, M. Rossi, V. De Martino, F. Marampon, Luca Borro, A. Secinaro, A. Del Fattore   +6 more
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

FAK-mediated mechanotransduction in skeletal regeneration [PDF]

, 2007
The majority of cells are equipped to detect and decipher physical stimuli, and then react to these stimuli in a cell type-specific manner. Ultimately, these cellular behaviors are synchronized to produce a tissue response, but how this is achieved ...
Kim Jae-Beom, Jill A Helms, Jennifer A Currey, Leucht Philipp, Helms, Jill A., Kim, Jae-Beom, Jae-Beom Kim, Leucht, Philipp, Currey Jennifer A., Brunski John, Helms Jill A., Currey, Jennifer A., Philipp Leucht, Brunski, John, John Brunski   +14 more
core   +2 more sources

The discovery and clinical significance of the “Twin Open Skylight and Summon Effects” of the Ilizarov tibial transverse transport technique

Гений oртопедии, 2021
Ilizarov’s tibial transverse transport (TTT) technique can promote vascular regeneration. It has been used in the treatment of a variety of lower limb ischemic diseases, such as thromboangiitis obliterans, diabetic foot ulcers, etc.
Weiwei Chen, Qikai Hua, Jinmin Zhao, Long Qu   +3 more
doaj   +1 more source

Osteogenic differentiation of adipose-derived canine mesenchymal stem cells seeded in porous calcium-phosphate scaffolds

Frontiers in Veterinary Science, 2023
IntroductionEngineered bone graft substitutes are a promising alternative and supplement to autologous bone grafts as treatments for bone healing impairment.
David Herrera, Irene Lodoso-Torrecilla, Maria-Pau Ginebra, Katrin Rappe, Jordi Franch   +4 more
doaj   +1 more source