Results 221 to 230 of about 216,236 (317)

Mineralized DNA tetrahedron-structured hydrogels: a dual-functional Scaffold for immunomodulation and bone regeneration. [PDF]

Bone Res
Yao L, Sun J, Liu Z, Liang J, Wang Y, Chen Y, Wang R, He T, Yang Y, He Y, Lin Y, Tian T.   +11 more
europepmc   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

Comparative mechanical characterisation of 13-93 bioactive glass and hybrid scaffolds for bone regeneration. [PDF]

Sci Rep
Liu J, Chen J, Heyraud A, Sharma A, Lamari M, Tallia F, Jones JR, Lee PD.   +7 more
europepmc   +1 more source

<p>Electrospun Poly (Aspartic Acid)-Modified Zein Nanofibers for Promoting Bone Regeneration</p>

, 2019
Yun Liu, Yingling Miao, Feng Qin, Cen Cao, Xiaolin Yu, Yuhan Wu, Tianlu Wang, Ruogu Xu, Zhao Liu, Fan Wu, Zhengchuan Zhang, Jiamin Yang, Yang Yang, Xin Xie, Liming Zhang, Feilong Deng   +15 more
openalex   +2 more sources

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Carp collagen membrane for guided bone regeneration: evaluation in a rat femoral defect model. [PDF]

Biomater Biosyst
Bujda M, Suchý T, Bartoš M, Lunáčková J, Dušková J, Žaloudková M, Foltán R.   +6 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

The roles of the nerve-immune axis in modulating bone regeneration. [PDF]

Bone Res
Zhao Y, Xu K, Wu K, Guo Z, Li H, Lin N, Ye Z, Huang X, Xu J, Huang D.   +9 more
europepmc   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Advanced multifunctional thermo- and electro-stimulative hydrogels for bone regeneration. [PDF]

Mater Today Bio
Zhang Y, Wang Y, Zou J, Huang J, Zhong Q, Xu Y, Lei M, Chen R, Wang D, Li H, Wang H, Wang J, Shi Z, Cheng H.   +13 more
europepmc   +1 more source