Silk-coated PLGA non-spherical microparticles for simvastatin delivery in rat maxillofacial bone regeneration. [PDF]
Zhang J +8 more
europepmc +1 more source
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley +1 more source
A composite hydrogel enables the spatiotemporal delivery of distinct cytokines to drive the native vascularized bone regeneration. [PDF]
Zhou C +17 more
europepmc +1 more source
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu +11 more
wiley +1 more source
HIF-1α and BMAL1 in bone regeneration: crosstalk between hypoxia response and circadian rhythm. [PDF]
Weng Y, Xiong J, Zhao Q, Tan Z.
europepmc +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Whitlockite as a next-generation biomaterial for bone regeneration: A systematic review of <i>In Vivo</i> evidence for bone regeneration. [PDF]
Palati S, Ganapathy D, Sekaran S.
europepmc +1 more source
Recent advances in biomaterials for bone regeneration: Bridging innovation and clinical translation. [PDF]
Sabouri Z +10 more
europepmc +1 more source
A neurovascularized bone regeneration strategy for mandibular and alveolar bone defects based on elastin-like biomaterials. [PDF]
Mahmoudi N +7 more
europepmc +1 more source

