Results 251 to 260 of about 216,236 (317)

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

Cyclic distraction-compression promotes bone regeneration during distraction osteogenesis through the Piezo1-YAP-β-catenin axis. [PDF]

Front Bioeng Biotechnol
Tang L, Jiang L, Liu J, Wu Y, Wang Z, Shen J, Yang J, Xian C, Wan Z, Liu K, Liu Y, Li Z.   +11 more
europepmc   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

Advanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian, Yanrui Yang, Qiuyu Li, Ying Hu, Qin Hu, Shasha Ran, Siyu Zhou, Xiujuan Yang, Shanshan Li, Qixiong Zhang   +9 more
wiley   +1 more source

Apoptotic-mimetic nanovesicles orchestrate immune-vascular-osteogenic crosstalk for critical-sized craniofacial bone regeneration. [PDF]

Mater Today Bio
Pan H, Zhang M, Chen L, Zhu H, Huang S, Huang Y, Li Y, Liu Z, Li X, Liu C.   +9 more
europepmc   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

3D-printed PCL scaffolds: optimising material selection for specific bone regeneration applications. [PDF]

J Mater Sci Mater Med
Rajzer I, Novotna R, Kurowska A, Janusz J, Fabia J, Jabłoński A, Piekarczyk W, Castano O, Ziąbka M, Frankova J.   +9 more
europepmc   +1 more source

Local bisphosphonate effect on bone regeneration. Systemic literature review

, 2019
Edgaras Baliūnas
openalex   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Sea Urchin-Inspired Immuno-Instructive Ionic Flow Drives MSCs-Macrophage Communication to Promote Bone Regeneration. [PDF]

Adv Mater
Lu Y, Su K, Liu D, Liu C, Qin M, Li S, Tian P, Wang Y, Wang Y, Chu L, Cui X, Pan H.   +11 more
europepmc   +1 more source