Results 281 to 290 of about 360,243 (347)

Beyond inflammation: the molecular basis of bone remodeling in axial spondyloarthritis and psoriatic arthritis. [PDF]

Front Immunol
Lopalco G, Cito A, Iannone F, Diekhoff T, Poddubnyy D, Proft F.   +5 more
europepmc   +1 more source

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

Synergistic Effect of Poly(ethylenephosphoric Acid) and Cerium in Bone Substitute Composites on Tissue Response and Bone Remodeling. [PDF]

Int J Mol Sci
Besprozvannykh V, Ryndyk M, Nifant'ev I, Tavtorkin A, Gavrilov D, Lukina Y, Bionyshev-Abramov L, Serejnikova N, Smolentsev D, Ivchenko P.   +9 more
europepmc   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

Impact of small antral pseudocyst interventions on bone remodeling during sinus floor elevation: a retrospective analysis. [PDF]

BMC Oral Health
Fu M, Yang F, Yu Y, Wu X, Zhou Q, Sun Y, Han Z, Song D, Yu Y.   +8 more
europepmc   +1 more source

Finite element analysis of bone remodeling induced by swelling anchors considering heterogeneous properties. [PDF]

Biomech Model Mechanobiol
Sadighi A, Taheri M, Black N, Stolle J, Taghvaei M, Boyes M, Siegler S, Schaer TP, Najafi AR.   +8 more
europepmc   +1 more source

Up-regulation of peripheral and central CGRP expression combined with subchondral bone remodeling in rat MIA-induced TMJOA model. [PDF]

J Oral Facial Pain Headache
Xu L, Jiang H, Xu Q, Fang W.
europepmc   +1 more source

Self-assembled DNA nanocarrier-enabled drug delivery for bone remodeling and antimicrobial applications. [PDF]

NPJ Biomed Innov
Huang J, Chakraborty A, Shamiya Y, Luo W, Zahid AA, Paul A.   +5 more
europepmc   +1 more source

Mechanosensitive miRNAs in Cartilage and Subchondral Bone Remodeling: Emerging Targets for Osteoarthritis Therapy. [PDF]

J Inflamm Res
Shang X.
europepmc   +1 more source

BMD, CTX-1, and Osteocalcin as Monitoring Parameters of Bone Remodelling in CML Patients Undergoing Imatinib Therapy: From Basic Science to Clinical Perspective

Nurita Indarwulan, Merlyna Savitri, Ami Ashariati, Ugroseno Yudho Bintoro, Muhammad Noor Diansyah, Putu Niken Ayu Amrita, Pradana Zaky Romadhon   +6 more
openalex   +2 more sources