Results 21 to 30 of about 1,254,785 (307)

Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC [PDF]

open access: yes, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam   +11 more
core   +1 more source

Experimental study of dexamethasone-loaded hollow hydroxyapatite microspheres applied to direct pulp capping of rat molars

open access: yesFrontiers in Endocrinology, 2023
BackgroundDexamethasone (DEX) exerts anti-inflammatory and osteogenic effects. Hydroxyapatite is commonly used in bone repair due to its osteoconductivity, osseointegration, and osteogenesis induction. Hollow hydroxyapatite (HHAM) is often used as a drug
Xiaoli Liu   +6 more
doaj   +1 more source

The bone remodelling cycle [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2018
The bone remodelling cycle replaces old and damaged bone and is a highly regulated, lifelong process essential for preserving bone integrity and maintaining mineral homeostasis. During the bone remodelling cycle, osteoclastic resorption is tightly coupled to osteoblastic bone formation.
JS Kenkre, JHD Bassett
openaire   +3 more sources

Quantitative Ultrasound of Cortical Bone in the Femoral Neck Predicts Femur Strength: Results of a Pilot Study [PDF]

open access: yes, 2013
Article first published online: 15 JAN 2013 Pour consulter la version éditeur DOI: 10.1002/jbmr.1742A significant risk of femoral neck (FN) fracture exists for men and women with an areal bone mineral density (aBMD) higher than the osteoporotic range ...
GRONDIN, Julien   +14 more
core   +1 more source

Macrophages and Bone Remodeling

open access: yesJournal of Bone and Mineral Research, 2023
ABSTRACT Bone remodeling in the adult skeleton facilitates the removal and replacement of damaged and old bone to maintain bone quality. Tight coordination of bone resorption and bone formation during remodeling crucially maintains skeletal mass. Increasing evidence suggests that many cell types beyond osteoclasts
Megan M Weivoda, Elizabeth W Bradley
openaire   +2 more sources

3D porous architecture of stacks of β-TCP granules compared with that of trabecular bone: a microCT, vector analysis and compression study

open access: yesFrontiers in Endocrinology, 2015
The 3D arrangement of porous granular biomaterials usable to fill bone defects has received little study. Granular biomaterials occupy 3D space when packed together in a manner that creates a porosity suitable for the invasion of vascular and bone cells.
Daniel eCHAPPARD   +6 more
doaj   +1 more source

Chemokines and Bone Remodeling

open access: yesInternational Journal of Immunopathology and Pharmacology, 2008
Bone remodeling is characterized by spatial and temporal coupling of bone resorption and formation and is necessary for skeletal growth and normal bone structure maintenance. Imbalance of this process is related to metabolic bone disorders such as osteoporosis or rheumatoid arthritis.
E. Galliera   +3 more
openaire   +3 more sources

Endothelialized tissue engineered 3D-construct for bone repair [PDF]

open access: yes, 2005
One of the main problems arising when implanting a graft into a large bone gap is its insufficient vascularization in the central region. This results in impaired bone healing and often leads to necrosis in the graft.
Meury, Thomas
core   +1 more source

The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation [PDF]

open access: yes, 2010
Background: Clock genes and their protein products regulate circadian rhythms in mammals but have also been implicated in various physiological processes, including bone formation.
Maronde, E. (Erik)   +33 more
core   +1 more source

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo [PDF]

open access: yes, 2008
Resident macrophages are an integral component of many tissues and are important in homeostasis and repair. This study examines the contribution of resident tissue macrophages to bone physiology.
Chang, M. K.   +28 more
core   +1 more source

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