Results 41 to 50 of about 1,254,785 (307)

Polyacrylamide-Sodium Alginate Hydrogel Releasing Oxygen and Vitamin C Promotes Bone Regeneration in Rat Skull Defects

Frontiers in Materials, 2021
Oxygen is essential for cell survival and tissue regeneration. Scaffolds releasing oxygen have been hypothesized as an ideal strategy for bone repair. However, excessive oxygen supply will disturb the redox balance, lead to oxidative stress, and affect ...
Bin Zhao, Bin Zhao, Jingya He, Jingya He, Feng Wang, Feng Wang, Ruxiao Xing, Ruxiao Xing, Bin Sun, Bin Sun, Yanmin Zhou, Yanmin Zhou   +11 more
doaj   +1 more source

Effect of oligonucleotide MT01 delivered by N-isopropylacrylamide modified polyethyleneimine for bone regeneration

Frontiers in Bioengineering and Biotechnology, 2023
Objective: This study aimed to investigate the regulatory effect of N-isopropylacrylamide-modified polyethyleneimine (PEN)-delivered oligodeoxynucleotide (ODN) MT01 on bone regeneration in vitro and in vivo.Methods: A polyethylenimine (PEI) derivative ...
Qian Zhang, Qian Zhang, Xingyuan Qu, Xingyuan Qu, Chen Liang, Chen Liang, Hongyan Li, Siyu Du, Siyu Du, Chang Wang, Chang Wang, Yuandong Xie, Yi Zheng, Lei Wang   +13 more
doaj   +1 more source

Immunoregulation of bone remodelling

International Journal of Critical Illness and Injury Science, 2012
Remodeling, a continuous physiological process maintains the strength of the bones, which maintains a delicate balance between bone formation and resorption process. This review gives an insight to the complex interaction and correlation between the bone remodeling and the corresponding changes in host immunological environment and also summarises the ...
Singh, Ajai, Mehdi, Abbass A, Srivastava, Rajeshwer N, Verma, Nar Singh   +3 more
openaire   +3 more sources

Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases

Frontiers in Oncology, 2023
Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. When bone homeostasis is broken, it can manifest as osteoarthritis (OA), rheumatoid arthritis (RA), osteosarcoma (OS), etc.
Shaotai Wang, Shaotai Wang, Min Hu, Min Hu, Dongsheng Song, Dongsheng Song, Linjun Tang, Huan Jiang, Huan Jiang   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Harnessing smart nanomaterials to reprogram neutrophil plasticity in immune modulation

Journal of Nanobiotechnology
Neutrophils are the most abundant type of white blood cells in the immune system and play a complex and intricate regulatory role in disease progression. Their critical contribution to maintaining homeostasis through migration, activation, and programmed
Jiaxin Luo, Jingxia Chen, Jing Zhou, Zhen Ci, Jian Feng, Xuyan Wei, Jingjie Zhai, Hanchi Wang, Yanmin Zhou   +8 more
doaj   +1 more source

D-methionine eradicates Porphyromonas gingivalis biofilms by suppressing the cyclic di-GMP level

口腔疾病防治, 2022
Objective To investigate the mechanisms by which D-methionine (D-Met) eradicates Porphyromonas gingivalis biofilms by suppressing cyclic dimeric GMP (c-di-GMP) levels.
XIE Lili, ZHANG Huiyan, WANG Zixuan, LI Birong, LI Zhen, MENG Weiyan   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Contribution of atypical chemokine receptor 2/ackr2 in bone remodeling

, 2017
Introduction: Bone remodeling is a tightly regulated process influenced by chemokines. ACKR2 is a decoy receptor for CC chemokines functioning as regulator of inflammatory response.
Sandra Yasuyo Fukada, Remo Castro Russo, Angélica Cristina Fonseca, Tarcília Aparecida da Silva, Davidson Frois Madureira, Janine Mayra da Silva, Letícia Fernanda Duffles Rodrigues, Izabella Lucas de Abreu Lima, Gustavo Pompermaier Garlet, Mauro Martins Teixeira   +9 more
core   +1 more source