Results 11 to 20 of about 217,854 (311)

Disorders of Bone Remodeling [PDF]

Annual Review of Pathology: Mechanisms of Disease, 2011
The skeleton provides mechanical support for stature and locomotion, protects vital organs, and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone modeling to carry out these crucial functions throughout life. Bone remodeling involves the removal of old or damaged bone by osteoclasts (bone resorption) and the ...
Xu, Feng, Jay M, McDonald
openaire   +3 more sources

A new comprehensive approach for bone remodeling under medium and high mechanical load based on cellular activity [PDF]

, 2020
The authors would like to thank the CNRS for its financial support through the Défi Mécanobiologie to carry out the work.Most of the last century, bone remodeling models have been proposed based on the observation that bone density is dependent on the ...
ALLENA, Rachele, GEORGE, Daniel, BENSIDHOUM, Morad, BOURZAC, Céline, PALLU, Stéphane, RÉMOND, Yves, PORTIER, Hugues   +6 more
core   +1 more source

Apoptotic mesenchymal stromal cells support osteoclastogenesis while inhibiting multinucleated giant cells formation in vitro

Scientific Reports, 2021
In bone regeneration induced by the combination of mesenchymal stromal cells (MSCs) and calcium-phosphate (CaP) materials, osteoclasts emerge as a pivotal cell linking inflammation and bone formation.
Paul Humbert, Meadhbh Á. Brennan, Julien De Lima, Régis Brion, Annie Adrait, Céline Charrier, Bénédicte Brulin, Valérie Trichet, Yohann Couté, Frédéric Blanchard, Pierre Layrolle   +10 more
doaj   +1 more source

The impact of masticatory dysfunction caused by occlusal disharmony on cognitive function

口腔疾病防治, 2021
As the world’s population ages, age-related cognitive decline and dementia are becoming important challenges for geriatric care. Despite the ongoing search for solutions to address cognitive decline, effective interventions have not yet been established.
OU Yanzhen, LI Baosheng, CAI Qing, JIANG Jiayang, JIN Zhuohua, MENG Weiyan   +5 more
doaj   +1 more source

Antibacterial properties of antimicrobial peptide HHC36 modified polyetheretherketone

Frontiers in Microbiology, 2023
IntroductionPolyetheretherketone (PEEK) is considered to be a new type of orthopedic implant material due to its mechanical properties and biocompatibility.
Weijia Gao, Xiao Han, Duo Sun, Yongli Li, Xiaoli Liu, Shihui Yang, Zhe Zhou, Yuanzheng Qi, Junjie Jiao, Jinghui Zhao   +9 more
doaj   +1 more source

SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression

Cells, 2020
Primary bone tumors can be divided into two classes, benign and malignant. Among the latter group, osteosarcoma and Ewing sarcoma are the most prevalent malignant primary bone tumors in children and adolescents.
Frédéric Lézot, Isabelle Corre, Sarah Morice, Françoise Rédini, Franck Verrecchia   +4 more
doaj   +1 more source

Chitosan as a biomaterial for the prevention and treatment of dental caries: antibacterial effect, biomimetic mineralization, and drug delivery

Frontiers in Bioengineering and Biotechnology, 2023
Dental caries is a chronic, progressive disease caused by plaque, influenced by multiple factors and can damage the hard tissues of the teeth. In severe cases, it can also lead to the onset and development of other oral diseases, seriously affecting ...
Shanlin Qu, Shanlin Qu, Xiaolin Ma, Xiaolin Ma, Shuo Yu, Shuo Yu, Rui Wang, Rui Wang   +7 more
doaj   +1 more source

The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem

Cells, 2020
Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children, adolescents, and young adults, and with a second peak of incidence in elderly individuals.
Isabelle Corre, Franck Verrecchia, Vincent Crenn, Francoise Redini, Valérie Trichet   +4 more
doaj   +1 more source

“Medicine food homology” plants promote periodontal health: antimicrobial, anti-inflammatory, and inhibition of bone resorption

Frontiers in Nutrition, 2023
“Medicine food homology” (MFH) is a term with a lengthy history. It refers to the fact that a lot of traditional natural products have both culinary and therapeutic benefits.
Shanlin Qu, Shanlin Qu, Shuo Yu, Shuo Yu, Xiaolin Ma, Xiaolin Ma, Rui Wang, Rui Wang   +7 more
doaj   +1 more source

Ribosomopathies: New Therapeutic Perspectives

Cells, 2020
Ribosomopathies are a group of rare diseases in which genetic mutations cause defects in either ribosome biogenesis or function, given specific phenotypes.
Emilien Orgebin, François Lamoureux, Bertrand Isidor, Céline Charrier, Benjamin Ory, Frédéric Lézot, Marc Baud’huin   +6 more
doaj   +1 more source