Results 61 to 70 of about 641,029 (315)

Gut microbiota and fecal metabolic signatures in rat models of disuse-induced osteoporosis

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundAssessing the correlation between gut microbiota (GM) and bone homeostasis has increasingly attracted research interest. Meanwhile, GM dysbiosis has been found to be associated with abnormal bone metabolism.
Xiaochen Qiao, Xiaochen Qiao, Xiaochen Qiao, Kun Zhang, Kun Zhang, Xiaoyan Li, Zhi Lv, Zhi Lv, Wenhao Wei, Wenhao Wei, Ruhao Zhou, Ruhao Zhou, Lei Yan, Lei Yan, Yongchun Pan, Sen Yang, Xiaojuan Sun, Xiaojuan Sun, Pengcui Li, Pengcui Li, Chaojian Xu, Chaojian Xu, Yi Feng, Yi Feng, Zhi Tian, Zhi Tian   +25 more
doaj   +1 more source

L-configuration re-attachment of distal biceps tendon rupture [PDF]

, 2009
In distal biceps tendon ruptures, re-attachment to the radial tuberosity should ensure adequate tendon to bone contact for optimal ...
Charalambous, CP, Funk, L, Gullett, TK, Philips, N, Ravenscroft, MJ   +4 more
core   +2 more sources

Substituted hydroxyapatites for bone repair

Journal of Materials Science: Materials in Medicine, 2012
Calcium phosphates such as hydroxyapatite have a wide range of applications both in bone grafts and for the coating of metallic implants, largely as a result of their chemical similarity to the mineral component of bone. However, to more accurately mirror the chemistry, various substitutions, both cationic (substituting for the calcium) and anionic ...
Jennifer H, Shepherd, David V, Shepherd, Serena M, Best   +2 more
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Integrated proteomics and metabolomics analysis of sclerosis-related proteins and femoral head necrosis following internal fixation of femoral neck fractures

Scientific Reports
Femoral head necrosis (FHN) is a serious complication after femoral neck fractures (FNF), often linked to sclerosis around screw paths. Our study aimed to uncover the proteomic and metabolomic underpinnings of FHN and sclerosis using integrated ...
Yang Liu, Yongsheng Ma, Wenming Yang, Qitai Lin, Yugang Xing, Huifeng Shao, Pengcui Li, Yong He, Wangping Duan, Xiaochun Wei   +9 more
doaj   +1 more source

Treatment of failed articular cartilage reconstructive procedures of the knee: A systematic review [PDF]

, 2018
Background: Symptomatic articular cartilage lesions of the knee are common and are being treated surgically with increasing frequency. While many studies have reported outcomes following a variety of cartilage restoration procedures, few have ...
Lamplot, Joseph D, Matava, Matthew J, Schafer, Kevin A   +2 more
core   +2 more sources

Cell therapy for bone repair

Orthopaedics & Traumatology: Surgery & Research, 2014
When natural bone repair mechanisms fail, autologous bone grafting is the current standard of care. The osteogenic cells and bone matrix in the graft provide the osteo-inductive and osteo-conductive properties required for successful bone repair. Bone marrow (BM) mesenchymal stem cells (MSCs) can differentiate into osteogenic cells.
P. Rosset, F. Deschaseaux, P. Layrolle
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Impairment of chondrocyte proliferation after exposure of young murine cartilage to an aged systemic environment in a heterochronic parabiosis model

Swiss Medical Weekly, 2018
AIM The aim of this study was to investigate whether an aged systemic environment could impair young cartilage tissue in mice. METHODS Mice differing in age were randomly divided into three groups ...
Lu Li, Xiaochun Wei, Xiang Geng, Zhiqing Duan, Xiaohu Wang, Pengcui Li, Chunfang Wang, Lei Wei   +7 more
doaj   +1 more source

Modulation of release kinetics by plasma polymerization of ampicillin-loaded ß-TCP ceramics [PDF]

, 2016
Beta-tricalcium phosphate (ß-TCP) bioceramics are employed in bone repair surgery. Their local implantation in bone defects puts them in the limelight as potential materials for local drug delivery.
Avilés, Marc, Buxadera Palomero, Judit, Canal Barnils, Cristina, Ginebra Molins, Maria Pau, Labay, Cédric Pierre   +4 more
core   +2 more sources