Results 41 to 50 of about 326,067 (120)

The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausal women with osteoporosis: a systematic review and meta-analysis of randomized controlled trials

open access: yesBMC Musculoskeletal Disorders
Purpose This systematic review and meta-analysis assesses the efficacy of combined calcium and vitamin D supplementation on bone mineral density (BMD) and fracture risk among postmenopausal women with osteoporosis.
Bo Cong, Haiguang Zhang
doaj   +1 more source

Key roles of the superficial zone in articular cartilage physiology, pathology, and regeneration

open access: yesChinese Medical Journal
. The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and mechanical stimuli. The SFZ is not only a crucial
Li Guo   +4 more
doaj   +1 more source

Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis

open access: yesEpigenetics & Chromatin
Background Histone modification H3K27me3 plays a critical role in normal development and is associated with various diseases, including cancer. This modification forms large chromatin domains, known as Large Organized Chromatin Lysine Domains (LOCKs ...
Yuan Liang   +9 more
doaj   +1 more source

Revealing key biomarkers and molecular mechanisms associated with di(2-ethylhexyl) phthalate in skin cancer

open access: yesFrontiers in Molecular Biosciences
BackgroundDi (2-ethylhexyl) phthalate (DEHP), the most widely used phthalate plasticizer, has been implicated in skin cancer. However, its key targets and multi-pathway mechanisms regulating skin cancer onset and progression remain unclear.
Haidong Zhou   +9 more
doaj   +1 more source

Research on stem cell therapy for spinal cord injury: a bibliometric and visual analysis from 2018–2023

open access: yesFrontiers in Genetics
Objectives: The aim of this study was to conduct a bibliometric analysis of the literature on stem cell treatment for spinal cord injury to gain an intuitive understanding of how the field is progressing, discover topics of interest, and determine what ...
Ruxing Liu   +16 more
doaj   +1 more source

High-speed centrifugation reduces immune rejection by removing bone marrow elements from fresh osteochondral allografts

open access: yesJournal of Orthopaedic Translation
Background: Fresh osteochondral allografts (OCAs) contain numerous immunogenic components in the subchondral bone (SB). Whether high-speed centrifugation (HSC) reduces immune rejection by removing bone marrow elements (BMEs), compared to methods without ...
Yongsheng Ma   +8 more
doaj   +1 more source

Proteomic analysis of endothelial progenitor cells secretome identifies Serpine 1 as a potent regulator of osteogenesis

open access: yesScientific Reports
Endothelial progenitor cells (EPCs) exert potent paracrine effect on bone regeneration, yet the specific protein mediators remain incompletely characterized.
Thabet Asbi   +9 more
doaj   +1 more source

Innovative 3D printing technologies and advanced materials revolutionizing orthopedic surgery: current applications and future directions

open access: yesFrontiers in Bioengineering and Biotechnology
Three-dimensional (3D) printing has rapidly become a transformative force in orthopedic surgery, enabling the creation of highly customized and precise medical implants and surgical tools.
Bo Cong   +3 more
doaj   +1 more source

Total body water percentage and 3rd space water are novel risk factors for training-related lower extremity muscle injuries in young males

open access: yesChinese Journal of Traumatology
Purpose: To identify the risk factors for training-related lower extremity muscle injuries in young males by a non-invasive method of body composition analysis. Methods: A total of 282 healthy young male volunteers aged 18 – 20 years participated in this
Liang Chen   +13 more
doaj   +1 more source

Clinical Outcomes and Safety of a Triple-Modality Approach Combining Decompression, Vertebral Augmentation, and Radiotherapy for Thoracolumbar Metastatic Tumors With Neurological Involvement

open access: yesJournal of Multidisciplinary Healthcare
Jian-Min Wang,1,2,* Pei-Sheng Liu,1,2,* De-Xin Zou,1,2 Jian-Feng Zhang,1,2 Tao Sun,2 Jun-Jie Jiang,2 Jian-Qing Liu,1,2 Wei Du1,2 1Department of Spine Surgery, Yantaishan Hospital Affiliated to Binzhou Medical University, Yantai, Shandong,
Wang JM   +7 more
doaj  

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