Results 31 to 40 of about 311,178 (265)

Pericytes for Therapeutic Bone Repair [PDF]

, 2018
Besides seminal functions in angiogenesis and blood pressure regulation, microvascular pericytes possess a latent tissue regenerative potential that can be revealed in culture following transition into mesenchymal stem cells. Endowed with robust osteogenic potential, pericytes and other related perivascular cells extracted from adipose tissue represent
Carolyn A, Meyers, Joan, Casamitjana, Leslie, Chang, Lei, Zhang, Aaron W, James, Bruno, Péault   +5 more
openaire   +2 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Ultra depth of field microscopy: a novel method for observing and characterizing of articular cartilage surface

Journal of Translational Medicine
Background The surface microstructures of cartilage are closely related to its functions. Accurate observation of cartilage surface is key to researching cartilage-related diseases.
Guohao Zhang, Ningning Ma, Jihao Wen, Tao Zhang, Ruxing Liu, Mengyu Fu, Li Guo, Xiaochun Wei   +7 more
doaj   +1 more source

The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway

Cells, 2020
Vascularization is a prerequisite for bone formation. Endothelial progenitor cells (EPCs) stimulate bone formation by creating a vascular network. Moreover, EPCs secrete various bioactive molecules that may regulate bone formation.
Tal Tamari, Rawan Kawar-Jaraisy, Ofri Doppelt, Ben Giladi, Nadin Sabbah, Hadar Zigdon-Giladi   +5 more
doaj   +1 more source

The administration of tranexamic acid for corrective surgery involving eight or more spinal levels: A systematic review and meta-analysis

Asian Journal of Surgery, 2022
As the number of fusion levels increases, the complexity of spinal correction surgery also increases. Thus, we conducted this study to determine the safety and efficacy of tranexamic acid (TXA) involving eight or more spinal fusion levels.
Lingan Huang, Pengcui Li, Xiaodong Gu, Ruipeng Zhao, Xiang Ma, Xiaochun Wei   +5 more
doaj   +1 more source

Cellular Mechanisms of Bone Repair

Journal of Investigative Surgery, 1997
The extent of callus formation about a bone fracture depends on the rigidity of fracture fixation. The mechanism that converts the mechanical stimulus into the biologic response is unknown. On the basis of existing literature, an attempt has been made to define a model that explains this mechanobiologic transduction. Once integrity of the bone has been
A, Probst, H U, Spiegel
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

GOLGB1 deficiency accelerates intervertebral disc degeneration by activating the MAPK pathway

Scientific Reports
Intervertebral disc degeneration (IDD) is a multifactorially regulated age-related condition. Golgin B1 (GOLGB1) is a large Golgi-related transmembrane protein encoded by golgb1 gene.
Jingyuan Tian, Zhiquan Wang, Ruxing Liu, Xiaoting Qiu, Dongqin He, Nan Shan, Qichao Li, Guanghui He, Bin Zhao, Jie Yuan, Yongfeng Wang   +10 more
doaj   +1 more source

A new device and method for detecting the permeability of articular cartilage

Frontiers in Bioengineering and Biotechnology
ObjectiveArticular cartilage relies on synovial fluid for substance exchange, with permeability being a key parameter linked to its physiological functions and degenerative disease mechanisms.
Fuyang Cao, Fuyang Cao, Haibin Deng, Haibin Deng, Guohao Zhang, Guohao Zhang, Ningning Ma, Ningning Ma, Binghang Zhang, Binghang Zhang, Xianda Che, Xianda Che, Gaige Wu, Gaige Wu, Pengcui Li, Pengcui Li, Li Guo, Li Guo, Xiaochun Wei, Xiaochun Wei   +19 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source