Results 21 to 30 of about 326,067 (120)

Ultra depth of field microscopy: a novel method for observing and characterizing of articular cartilage surface

Journal of Translational Medicine
Background The surface microstructures of cartilage are closely related to its functions. Accurate observation of cartilage surface is key to researching cartilage-related diseases.
Guohao Zhang, Ningning Ma, Jihao Wen, Tao Zhang, Ruxing Liu, Mengyu Fu, Li Guo, Xiaochun Wei   +7 more
doaj   +1 more source

The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway

Cells, 2020
Vascularization is a prerequisite for bone formation. Endothelial progenitor cells (EPCs) stimulate bone formation by creating a vascular network. Moreover, EPCs secrete various bioactive molecules that may regulate bone formation.
Tal Tamari, Rawan Kawar-Jaraisy, Ofri Doppelt, Ben Giladi, Nadin Sabbah, Hadar Zigdon-Giladi   +5 more
doaj   +1 more source

GOLGB1 deficiency accelerates intervertebral disc degeneration by activating the MAPK pathway

Scientific Reports
Intervertebral disc degeneration (IDD) is a multifactorially regulated age-related condition. Golgin B1 (GOLGB1) is a large Golgi-related transmembrane protein encoded by golgb1 gene.
Jingyuan Tian, Zhiquan Wang, Ruxing Liu, Xiaoting Qiu, Dongqin He, Nan Shan, Qichao Li, Guanghui He, Bin Zhao, Jie Yuan, Yongfeng Wang   +10 more
doaj   +1 more source

A new device and method for detecting the permeability of articular cartilage

Frontiers in Bioengineering and Biotechnology
ObjectiveArticular cartilage relies on synovial fluid for substance exchange, with permeability being a key parameter linked to its physiological functions and degenerative disease mechanisms.
Fuyang Cao, Fuyang Cao, Haibin Deng, Haibin Deng, Guohao Zhang, Guohao Zhang, Ningning Ma, Ningning Ma, Binghang Zhang, Binghang Zhang, Xianda Che, Xianda Che, Gaige Wu, Gaige Wu, Pengcui Li, Pengcui Li, Li Guo, Li Guo, Xiaochun Wei, Xiaochun Wei   +19 more
doaj   +1 more source

The administration of tranexamic acid for corrective surgery involving eight or more spinal levels: A systematic review and meta-analysis

Asian Journal of Surgery, 2022
As the number of fusion levels increases, the complexity of spinal correction surgery also increases. Thus, we conducted this study to determine the safety and efficacy of tranexamic acid (TXA) involving eight or more spinal fusion levels.
Lingan Huang, Pengcui Li, Xiaodong Gu, Ruipeng Zhao, Xiang Ma, Xiaochun Wei   +5 more
doaj   +1 more source

Deficient gait function despite effect index of the Western Ontario and McMaster university osteoarthritis index score considered cured one year after bilateral total knee arthroplasty

BMC Musculoskeletal Disorders
Background To clarify the value of gait analysis and its consistency with traditional scoring scales for the evaluation of knee joint function after total knee arthroplasty (TKA). Methods This study included 25 patients with knee osteoarthritis (KOA) who
Ruipeng Zhao, Xiaochun Wei, Shuai Hu, Yixuan Zhang, Hongru Wu, Pengcui Li, Yu Zhao   +6 more
doaj   +1 more source

Integrated proteomics and metabolomics analysis of sclerosis-related proteins and femoral head necrosis following internal fixation of femoral neck fractures

Scientific Reports
Femoral head necrosis (FHN) is a serious complication after femoral neck fractures (FNF), often linked to sclerosis around screw paths. Our study aimed to uncover the proteomic and metabolomic underpinnings of FHN and sclerosis using integrated ...
Yang Liu, Yongsheng Ma, Wenming Yang, Qitai Lin, Yugang Xing, Huifeng Shao, Pengcui Li, Yong He, Wangping Duan, Xiaochun Wei   +9 more
doaj   +1 more source

Heel hidradenocarcinoma regarded as a corn for 25 years with subsequent multiorgan metastasis: a case report and literature review

Frontiers in Oncology
BackgroundHidradenocarcinoma is a rare malignant cutaneous adnexal tumor with nonspecific clinical features. Heel involvement is uncommon and may be mistaken for a benign hyperkeratotic or pressure-related lesion.Case presentationA 44-year-old woman was ...
Lianbo Yang, Ziang Zheng, Haoran Chen, Xinyao Cui, Jiabin Lin, Yifan Wang, Haidong Liang, Jing Yi   +7 more
doaj   +1 more source

Impairment of chondrocyte proliferation after exposure of young murine cartilage to an aged systemic environment in a heterochronic parabiosis model

Swiss Medical Weekly, 2018
AIM The aim of this study was to investigate whether an aged systemic environment could impair young cartilage tissue in mice. METHODS Mice differing in age were randomly divided into three groups ...
Lu Li, Xiaochun Wei, Xiang Geng, Zhiqing Duan, Xiaohu Wang, Pengcui Li, Chunfang Wang, Lei Wei   +7 more
doaj   +1 more source

LMK-235 suppresses osteoclastogenesis and promotes osteoblastogenesis by inhibiting HDAC4

Scientific Reports
Osteoblasts and osteoclasts play an important role in maintaining the structural integrity of bone tissue, in which osteoclasts degrade bone structure and osteoblasts restore bone tissue.
Chongwei Chen, Yue Li, Teng Feng, Xinping Chen, Chengwei Li, Lu Li, Mengbo Zhu, Yaqiong Chang, Shaowei Wang   +8 more
doaj   +1 more source