Results 111 to 120 of about 1,831,965 (356)
The Role of Transforming Growth Factor Beta-1 in Bone Remodeling [PDF]
, 2009 Bone remodeling depends on the precise coordination of bone resorption by the osteoclasts and bone formation by the osteoblasts. It is proposed that osteoclastic bone resorption releases factors to initiate bone formation, thereby, coupling the bone ...
Tang, Yi
core +1 more source
Impact of cytokines and T lymphocytes upon osteoclast differentiation and function [PDF]
, 2007 Historically, the osteoblast has been considered the master cell in the control of osteoclast development and, therefore, bone resorption. Now the interactions between cells of the immune system and bone cells have redefined our thinking on the ...
Gillespie, Matthew T
core +3 more sources
miR-31 controls osteoclast formation and bone resorption by targeting RhoA
Arthritis Research & Therapy, 2013 IntroductionIncreased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated.
F. Mizoguchi +4 more
semanticscholar +1 more source
A Bio‐Inspired Perspective on Materials Sustainability
Advanced Materials, EarlyView.This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier +2 more
wiley +1 more source
Bone Remodeling as a Spatial Evolutionary Game [PDF]
arXiv, 2016 Bone remodeling is a complex process involving cell-cell interactions, biochemical signaling and mechanical stimuli. Early models of the biological aspects of remodeling were non-spatial and focused on the local dynamics at a fixed location in the bone.
arxiv
Breast Cancer Induced Bone Osteolysis Prediction Using Temporal Variational Auto-Encoders [PDF]
arXiv, 2022 Objective and Impact Statement. We adopt a deep learning model for bone osteolysis prediction on computed tomography (CT) images of murine breast cancer bone metastases. Given the bone CT scans at previous time steps, the model incorporates the bone-cancer interactions learned from the sequential images and generates future CT images.
arxiv
Materials Advances in Devices for Heart Disease Interventions
Advanced Materials, EarlyView.This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra +11 more
wiley +1 more source
RACK1 interaction with c-Src is essential for osteoclast function
Experimental and Molecular Medicine, 2019 Bone disease: scaffolding protein essential for bone resorption The interaction between RACK1, a so-called scaffolding protein that can assemble components of a signaling pathway into complexes, and c-Src, an enzyme involved in the re-organization of the
Jin Hee Park +9 more
doaj +1 more source
A phase field approach to trabecular bone remodeling [PDF]
arXiv, 2017 We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for local bone formation and resorption.
arxiv
Journal of Clinical Endocrinology and Metabolism, 2013 OBJECTIVE Our objective was to characterize changes in bone resorption in relation to the final menstrual period (FMP), reproductive hormones, body mass index (BMI), and ethnicity. METHODS Urinary type I collagen N-telopeptide (NTX), estradiol, and FSH
M. Sowers +7 more
semanticscholar +1 more source