Results 81 to 90 of about 1,847,810 (404)

Focusing on OB-OC-MΦ Axis and miR-23a to Explore the Pathogenesis and Treatment Strategy of Osteoporosis

open access: yesFrontiers in Endocrinology, 2022
Osteoporosis is a bone metabolic disorder characterized by decreased bone density and deteriorated microstructure, which increases the risk of fractures.
Tian-Liang Ma   +9 more
doaj   +1 more source

The Role of Osteocytes in Targeted Bone Remodeling: A Mathematical Model [PDF]

open access: yesPLoS ONE 2013 May 22; 8(5): e63884, 2012
Until recently many studies of bone remodeling at the cellular level have focused on the behavior of mature osteoblasts and osteoclasts, and their respective precursor cells, with the role of osteocytes and bone lining cells left largely unexplored. This is particularly true with respect to the mathematical modeling of bone remodeling.
arxiv   +1 more source

Genistein Prevents Bone Resorption Diseases by Inhibiting Bone Resorption and Stimulating Bone Formation

open access: yesBiological and Pharmaceutical Bulletin, 2003
Genistein, a soybean-derived isoflavone, has been shown to suppress osteoclastic bone resorption. To clarify the mechanisms underlying this action, we investigated the effects of genistein on the differentiation, cytoskeleton and function in mice osteoclasts in vitro and bone metabolism in ovariectomized rats.Primary OCs were isolated from 3 week-old ...
Shifeng Yu, Binbin Li
openaire   +3 more sources

Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2014
BACKGROUND In humans, the pronounced postprandial reduction in bone resorption (decreasing bone resorption markers by around 50%) has been suggested to be caused by gut hormones.
A. Nissen   +5 more
semanticscholar   +1 more source

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik   +2 more
wiley   +1 more source

Polymethoxy Flavonoids, Nobiletin and Tangeretin, Prevent Lipopolysaccharide-Induced Inflammatory Bone Loss in an Experimental Model for Periodontitis

open access: yesJournal of Pharmacological Sciences, 2012
Nobiletin, a polymethoxy flavonoid (PMF), inhibits systemic bone resorption and maintains bone mass in estrogen-deficient ovariectomized mice. This study examined the antiinflammatory effects of PMFs, nobiletin, and tangeretin on lipopolysaccharide (LPS)-
Tsukasa Tominari   +4 more
doaj  

Capture the fracture - use of bone turnover markers in clinical practice [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2016
Bone is a living tissue, metabolically very active, with the level of turnover of about 10% per year. Bone remodeling is a well-balanced process of bone resorption, induced by osteoclasts and bone formation maintained osteoblasts.
Vuksanović Miljanka   +1 more
doaj   +1 more source

Bone Adaptation as a Geometric Flow [PDF]

open access: yesarXiv, 2021
This paper presents bone adaptation as a geometric flow. The proposed method is based on two assumptions: first, that the bone surface is smooth (not fractal) permitting the definition of a tangent plane and, second, that the interface between marrow and bone tissue phases is orientable.
arxiv  

Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts

open access: yesJournal of Bone Metabolism, 2014
Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone disease such as osteoporosis ensues.
K. Ikeda, S. Takeshita
semanticscholar   +1 more source

An In Situ Curing, Shear‐Responsive Biomaterial Designed for Durable Embolization of Microvasculature

open access: yesAdvanced Healthcare Materials, EarlyView.
NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham   +16 more
wiley   +1 more source

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