Results 81 to 90 of about 92,559 (349)

Filling bone defects with β-TCP in maxillofacial surgery: A review [PDF]

, 2017
Reconstruction of bone defects prior to implant placement now involves synthetic substitutes such as β-TCP because of its ability to promote bone remodeling.
B. Guillaume
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review

Orthopedic Research and Reviews, 2011
Larry E Miller1,2, Jon E Block21Miller Scientific Consulting, LLC, Flagstaff, AZ, USA; 2Jon E. Block, Ph.D., Inc., San Francisco, CA, USAAbstract: A variety of bone grafts and bone graft substitutes is available for treatment of osseous defects although ...
Miller LE, Block JE
doaj  

Preclinical investigation of an innovative magnesium-based bone graft substitute for potential orthopaedic applications

Journal of Orthopaedic Translation, 2014
Degradable or corrosive biometal is an attractive research and development (R&D) area in clinical orthopaedics. This study was designed to investigate biomechanical and biological properties of magnesium (Mg) and strontium (Sr) with a focus on Mg-based ...
Chen Liu, Peng Wan, Li Li Tan, Kehong Wang, Ke Yang   +4 more
doaj   +1 more source

Bone healing in extraction sockets covered with collagen membrane alone or associated with porcine-derived bone graft: a comparative histological and histomorphometric analysis [PDF]

, 2017
The present paper reports data of a randomized study aimed to analyse and compare the histologic and histomorphometric aspects of bone healing in extraction sites covered with collagen membrane alone or associated with porcine-derived bone ...
De Angelis, Francesca, Di Carlo, Stefano, Guarnieri, Renzo, Mencio, Francesca, Pompa, Giorgio, Stefanelli, Luigi, Testarelli, Luca   +6 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices [PDF]

, 2015
Journal of Osseointegration Volume 7, Issue 1, 1 March 2015, Pages 2-7 Open Access Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices (Article) Pozzuoli, A.a, Gardin, C.b, Aldegheri, R.a, Bressan, E.c,
Aldegheri, R., Arrigoni, P., Biz, Carlo, Bressan, Eriberto, Calvo Guirado, J. L., Feroni, L., Gardin, Chiara, Isola, Maurizio, Pozzuoli, Assunta, Zavan, Barbara   +9 more
core   +1 more source

Bone substitutes in the Netherlands - A systematic literature review [PDF]

, 2011
Autologous bone grafting is currently considered as the gold standard to restore bone defects.
El-Massoudi, Y. (Youssef), Kralingen, G.H. (Gerdine) van, Lieshout, E.M.M. (Esther) van, Patka, P. (Peter), Stok, J. (Johan) van der   +4 more
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Review Article: Bone Transplantation and Immune Response

Journal of Orthopaedic Surgery, 2009
Bone is the second most common transplant tissue after blood, with the iliac crest autologous graft being most used. Bone transplantation induces osteogenesis to repair bone defects.
Hamid Shegarfi, Olav Reikeras
doaj   +1 more source