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Nanobiomaterials for Bone Tissue Engineering
2019Biomaterials with functional properties are used to fabricate scaffolds for bone tissue engineering. Several of these materials can be derived from nature, processed and transformed into regenerative scaffolds and/or artificial matrices for applications in bone tissue repair or regeneration.
Lowe, Baboucarr +5 more
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Apoptosis in Bone for Tissue Engineering
Archives of Medical Research, 2008Bone loss due to congenital defects, trauma, improper fracture fixation, metabolic disturbances, infections, or after tumor resection represents a major clinical problem in head and neck surgery. To address these issues, different types of scaffolds, growth factors and cell sources -- alone or in various combinations -- have been applied for ...
Gregor M, Bran +4 more
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Boning up on tissue engineering
Trends in Biotechnology, 2000The past two years have been an exciting time for the field of tissue engineering. There have been remarkable advances in eliciting the full developmental potential of stem cells from a number of mammalian tissues. In addition, the generation of human embryonic stem cell lines heralds a future in which a variety of tissues can be generated in culture ...
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Osteoclastogenesis on Tissue-Engineered Bone
Tissue Engineering, 2004Bone remodeling plays an important role in bone function. To date, bone tissue-engineering research has focused primarily on bone formation from osteoblasts. This study demonstrates that osteoclastogenesis can occur on a mineralized polymer scaffold. Porcine bone marrow-derived mesenchymal stem cells (pMSCs) and hematopoietic cells were isolated from ...
Keisuke, Nakagawa +5 more
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Bone And Cartilage Tissue Engineering
Clinics in Plastic Surgery, 1999Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centered on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy.
B D, Boyan +3 more
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Craniofacial bone tissue engineering
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2012There are numerous conditions, such as trauma, cancer, congenital malformations, and progressive deforming skeletal diseases, that can compromise the function and architectonics of bones of craniofacial region. The need to develop new approaches for treatment of these disorders arises from the fact that conventional therapeutic strategies face many ...
Vladimir, Petrovic +3 more
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Bioreactors for bone tissue engineering
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 2010Engineering bone tissue for use in orthopaedics poses multiple challenges. Providing the appropriate growth environment that will allow complex tissues such as bone to grow is one of these challenges. There are multiple design factors that must be considered in order to generate a functional tissue in vitro for replacement surgery in the clinic ...
El Haj, AJ +1 more
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Bone tissue engineering in osteoporosis
Maturitas, 2013Osteoporosis is a polygenetic, environmentally modifiable disease, which precipitates into fragility fractures of vertebrae, hip and radius and also confers a high risk of fractures in accidents and trauma. Aging and the genetic molecular background of osteoporosis cause delayed healing and impair regeneration.
Franz Jakob +6 more
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Optimization of bone‐tissue engineering in goats
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2004AbstractSuccessful bone‐tissue engineering (TE) has been reported for various strategies to combine cells with a porous scaffold. In particular, the period after seeding until implantation of the constructs may vary between hours and several weeks. Differences between these strategies can be reduced to (a) the presence of extracellular matrix, (b) the ...
Kruyt, Moyo C. +5 more
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Preclinical Imaging in Bone Tissue Engineering
Tissue Engineering Part B: Reviews, 2014Since X-rays were discovered, in 1895, and since the first radiological image of a hand, bone tissue has been the subject of detailed medical imaging. However, advances in bone engineering, including the increased complexity of implant scaffolds, currently also underline the limits of X-ray imaging.
Ventura, M. +8 more
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