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Peptides for bone tissue engineering
Journal of Controlled Release, 2016Molecular signals in the form of growth factors are the main modulators of cell behavior. However, the use of growth factors in tissue engineering has several drawbacks, including their costs, difficult production, immunogenicity and short half-life. Furthermore, many of them are pleiotropic and, since a single growth factor can have different active ...
Rick, Visser +3 more
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Electrospinning for Bone Tissue Engineering
Recent Patents on Nanotechnology, 2008Bone tissue engineering is a field of significant research interest owing to the large number of bone defects and the limitations in the present techniques to effectively reconstitute the defects. Cell-based bone graft technique has shown promise in overcoming the limitations of the other bone graft techniques currently used.
Koushik, Ramachandran +1 more
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Osteoclastogenesis on Tissue-Engineered Bone
Tissue Engineering, 2004Bone remodeling plays an important role in bone function. To date, bone tissue-engineering research has focused primarily on bone formation from osteoblasts. This study demonstrates that osteoclastogenesis can occur on a mineralized polymer scaffold. Porcine bone marrow-derived mesenchymal stem cells (pMSCs) and hematopoietic cells were isolated from ...
Keisuke, Nakagawa +5 more
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Bone And Cartilage Tissue Engineering
Clinics in Plastic Surgery, 1999Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centered on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy.
B D, Boyan +3 more
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Bioreactors for bone tissue engineering
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 2010Engineering bone tissue for use in orthopaedics poses multiple challenges. Providing the appropriate growth environment that will allow complex tissues such as bone to grow is one of these challenges. There are multiple design factors that must be considered in order to generate a functional tissue in vitro for replacement surgery in the clinic ...
El Haj, AJ, Cartmell, SH
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Bone tissue engineering in osteoporosis
Maturitas, 2013Osteoporosis is a polygenetic, environmentally modifiable disease, which precipitates into fragility fractures of vertebrae, hip and radius and also confers a high risk of fractures in accidents and trauma. Aging and the genetic molecular background of osteoporosis cause delayed healing and impair regeneration.
Franz Jakob +6 more
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Boning up on tissue engineering
Trends in Biotechnology, 2000The past two years have been an exciting time for the field of tissue engineering. There have been remarkable advances in eliciting the full developmental potential of stem cells from a number of mammalian tissues. In addition, the generation of human embryonic stem cell lines heralds a future in which a variety of tissues can be generated in culture ...
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Preclinical Imaging in Bone Tissue Engineering
Tissue Engineering Part B: Reviews, 2014Since X-rays were discovered, in 1895, and since the first radiological image of a hand, bone tissue has been the subject of detailed medical imaging. However, advances in bone engineering, including the increased complexity of implant scaffolds, currently also underline the limits of X-ray imaging.
Ventura, M. +8 more
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