Results 201 to 210 of about 479,728 (360)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Cases of nasal deformity treated by bone transplantation. Dr. W. W. Carter. published in the present issue of the laryngoscope.

, 1915
W. W. Carter
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Analysis of the therapeutic effect of allogeneic hematopoietic stem cell transplantation in the treatment of pediatric acute lymphoblastic leukemia with <i>E2A::HLF</i> fusion gene: a case series. [PDF]

Transl Pediatr
Jing Y, Wei A, Jia C, Yang J, Zhu G, Luo Y, Zhang K, Yang W, Chen W, Zhang M, Qin M, Wang B.   +11 more
europepmc   +1 more source

Interior Decorative VOCs Elevate T Cell‐Mediated Obstructive Lung Disease Risks via Osteogenesis‐Driven Lymphoid‐Biased Hematopoiesis

Advanced Science, EarlyView.
This study utilizes a whole‐body inhalation model to reveal that interior decorative VOCs exposure persistently elevates alveolar T cells. This increase is attributed to lymphoid‐biased hematopoiesis in the bone marrow, which is further driven by IL‐6/IL‐17A‐mediated osteogenic differentiation.
Hongyan Yu, Jingxu Zhang, Qingping Liu, Duxing Li, Ruonan Pan, Gan Miao, Yidi Chen, Zhe Kou, Guangbo Qu, Rong Zhang, Xiaoting Jin, Yuxin Zheng   +11 more
wiley   +1 more source

G-CSF Priming of Haploidentical Bone Marrow: Effects on Cell Yield, Collection Efficiency, and Tolerogenic Graft Composition. [PDF]

Ann Transplant
Duraković N, Babić A, Desnica L, Perić Z, Serventi Seiwerth R, Batinić D, Vrhovac R.   +6 more
europepmc   +1 more source

Hyperparathyroidism after kidney homotransplantation [PDF]

, 1987
Geis, WP, Hammond, WS, Huffer, WE, Popovtzer, MM, Starzl, TE   +4 more
core  

Methodologies for Sample Multiplexing and Computational Deconvolution in Single‐Cell Sequencing

Advanced Science, EarlyView.
Sample multiplexing offers a critical solution for boosting throughput and minimizing batch effects in single‐cell sequencing. This review navigates the latest experimental methodologies and computational deconvolution algorithms, bridging the gap between wet‐lab design and analytical success.
Yufei Gao, Weiwei Yin, Wei Hu, Wei Chen
wiley   +1 more source

Modified vascularised posterior inter-trochanteric bone grafting technique for the treatment of femoral head necrosis: a technical note with 2-year follow-up based on cadaveric models. [PDF]

BMC Surg
Zhang Y, Ma T, Jiang C, Hua B, Cao L, Yan Z.   +5 more
europepmc   +1 more source

Principles of transplantation [PDF]

, 1998
Reyes, J, Starzl,
core