Results 211 to 220 of about 479,728 (360)

Histological findings of the extraction socket (day 7). (A) Overview. (B) Control group, (C) transplanted group. The extraction sockets in both groups were filled with blood clots (arrows) and granulation tissue composed of inflammatory cells (neutrophils and macrophages) and fibroblasts (arrowheads). Moreover, new bone formation (*) was observed in the transplant group. Scale bars; (A) 300 µm (B, C) 200 µm.

Kohei Ijichi (21656230), Reiko Tokuyama-Toda (6744080), Mai Takeshita-Umehara (21656233), Toshio Yudo (21656236), Yusuke Takebe (6744074), Kazuhito Satomura (599629)   +5 more
openalex   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Augmenting Bone Formation by Implanting Dedifferentiated Fat Cell-Loaded Cotton-like Graft Materials in a Rat Bone Defect Model. [PDF]

Bioengineering (Basel)
Inoue J, Kazama T, Okubo T, Akita D, Arai Y, Hagiwara Y, Kano K, Honda M, Matsumoto T.   +8 more
europepmc   +1 more source

Immunity against Pseudomonas aeruginosa adoptively transferred to bone marrow transplant recipients [PDF]

, 1990
David Gottlieb, S J Cryz, E Fürer, JU Que, H. G. Prentice, A. S. Duncombe, MK Brenner   +6 more
openalex   +1 more source

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

<i>Rbfox2</i> selectively governs hematopoietic stem cell self-renewal by regulating proteostasis. [PDF]

Sci Adv
Gao L, Dickson D, Feng H, Zhang C, Ding L.   +4 more
europepmc   +1 more source

407: Predictive factors for engraftment in bone marrow transplant recipients [PDF]

, 2007
Zandra Rivera, Alison Gulbis, Marcos de Lima, Gabriela Rondón   +3 more
openalex   +1 more source

Bone Marrow Mesenchymal Stem Cell Hydrogel‐Mediated Fibroblast Reprogramming Restores Intestinal Function in Adhesive Small Bowel Obstruction

Advanced Science, EarlyView.
Conceptual diagram and schematic illustration of microenvironmental changes in individuals with ASBO before and after treatment. BMSC@Gel therapy transforms the ASBO microenvironment from an inflammatory, fibrotic state with aberrant matrix deposition and barrier dysfunction to a regenerative state with reduced inflammation and improved structural ...
Lihong Zheng *, Junrong Zhang *, Zhengyuan Huang *, Zhenliang Lin, Jin Zhang, Da Zhang, Ping Hou, Xianqiang Chen   +7 more
wiley   +1 more source

Adult duck fecal microbiota transplantation alleviates short beak and dwarfism syndrome in ducklings by inhibiting Th17 cell differentiation. [PDF]

Virulence
Liu M, Liu W, Zhao K, Zhang W, Lei B, Zhang Y, Li L, Yuan W.   +7 more
europepmc   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source