Results 61 to 70 of about 2,993,509 (396)

Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells

Stem Cell Research & Therapy, 2023
Background In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of the dorsal aorta and subsequently migrate to secondary niches where they expand and differentiate into committed lineages.
Honghu Li, Qian Luo, Shuyang Cai, Ruxiu Tie, Ye Meng, Wei Shan, Yulin Xu, Xiangjun Zeng, Pengxu Qian, He Huang   +9 more
doaj   +1 more source

AUTOPLASTIC TRANSPLANTATION OF BONE

Annals of Surgery, 1910
n ...
openaire   +3 more sources

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Injectable hydrogels for cartilage and bone tissue engineering

Bone Research, 2017
Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture ...
Mei Liu, Xin-Peng Zeng, Chao Ma, Huan Yi, Zeeshan Ali, Xianbo Mou, Song Li, Yan Deng, N. He   +8 more
semanticscholar   +1 more source

Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]

, 1989
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone, A.L. Hoffman, B.F. Banner, Barclay A, Berenson R J, Beschorner W E, Bril H, D.G. Sheahan, D.V. Cramer, Dallman M J, Elkins W L, Farnsworth A, Filipovich A H, Kvalheim G, L. Makowka, Lubaroff D M, Martin P J, Monchik G J, Oaks M K, P. Rettinger, Prentice H G, Reisner Y, Rodt H, Slavin R E, T.E. Starzl, Thtschka P J, Tsoi M-S, Van Bekkum D W, Vartdal F, Waldman H, X. Cai   +30 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE2

Stem Cell Research & Therapy, 2017
Background Bone marrow mesenchymal stem cells (MSCs) are promising candidates for the treatment of various inflammatory disorders due to their profound immunomodulatory properties.
Binsheng Wang, Yu Lin, Yongxian Hu, Wei Shan, Senquan Liu, Yulin Xu, Hao Zhang, Shuyang Cai, Xiaohong Yu, Zhen Cai, He Huang   +10 more
doaj   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

Nature Communications, 2018
Bone regeneration relies on the activation of skeletal stem cells (SSCs) that still remain poorly characterized. Here, we show that periosteum contains SSCs with high bone regenerative potential compared to bone marrow stromal cells/skeletal stem cells ...
Oriane Duchamp de Lageneste, Anais Julien, Rana Abou-Khalil, G. Frangi, C. Carvalho, N. Cagnard, C. Cordier, S. Conway, C. Colnot   +8 more
semanticscholar   +1 more source