Results 171 to 180 of about 2,694,526 (308)

Reframing the starting point of shared decision-making under algorithmic short-form video exposure: bone tumor care as a sentinel context. [PDF]

Front Public Health
Wang JW, Feng YF, Zhang ZB.
europepmc   +1 more source

Tumor Dormancy in The Bone

, 2020
Ottewell, P.D., Quayle, L.A.
openaire   +2 more sources

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Reawakening of a Giant Cell Bone Tumor after 40 Years of Silence: A Rare Case Report. [PDF]

J Orthop Case Rep
Karagergou E, Mountzouris M, Givissis A, Givissis P.   +3 more
europepmc   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

Advanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Correction: Application of a rapid and accurate safe-margin volume generation method in computer-assisted bone tumor resection surgery. [PDF]

J Orthop Surg Res
Zhang Y, Pang D, Li Z, Sun Y, Liu W, Zhang Q.   +5 more
europepmc   +1 more source

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

Advanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang, Min Li, Zhiying Yao, Yu Hu, Zhili Wang, Wendi Shi, Bingbing Sun   +6 more
wiley   +1 more source

Xanthogranulomatous Osteomyelitis as a Bone Tumor Mimic: A Systematic Review of Pre-biopsy Diagnostic Clues and Management Decision Points. [PDF]

Cureus
Sack EJ, Deneroff M, Khau A, Mohammed Z, Ellaham C, Nichols JW.   +5 more
europepmc   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

Multi-Omics-Guided Discovery of <i>Holothuria scabra</i>-Derived Drug Candidates Targeting Ferroptosis and the Bone Tumor Microenvironment in Osteosarcoma. [PDF]

Mar Drugs
Sibarani JN, Khumaidi MA, Sakti YM, Permatasari HK, Hendrawan AF, Surya R, Millotti G, Hadinata E, Kovačić I, Tjandrawinata RR, Nurkolis F.   +10 more
europepmc   +1 more source