Results 91 to 100 of about 3,258,179 (313)

Unraveling the glyco-puzzle : glycan structure identification by capillary electrophoresis [PDF]

, 2013
State-of-the-art high-resolution separation techniques play an important role in the full structural elucidation of glycans. Capillary electrophoresis (CE) offers a rapid yet simple method for exhaustive carbohydrate profiling.
Bones, Jonathan, Guttman, András, Mittermayr, Stefan   +2 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Segmentation of bone structures in 3D CT images based on continuous max- ow optimization [PDF]

, 2015
In this paper an algorithm to carry out the automatic segmentation of bone structures in 3D CT images has been implemented. Automatic segmentation of bone structures is of special interest for radiologists and surgeons to analyze bone diseases or to ...
Acha Piñero, Begoña, Pérez Carrasco, José Antonio, Serrano Gotarredona, María del Carmen   +2 more
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Evaluating the Anti-Osteoporotic Potential of Mediterranean Medicinal Plants: A Review of Current Evidence

Pharmaceuticals
Background: Bones are biological reservoirs for minerals and cells, offering protection to the other organs and contributing to the structural form of the body.
Alhareth Abdulraheem Al-Ajalein, Nurul ‘Izzah Ibrahim, Mh Busra Fauzi, Sabarul Afian Mokhtar, Isa Naina Mohamed, Ahmad Nazrun Shuid, Norazlina Mohamed   +6 more
doaj   +1 more source

Ethnochemistry in the Dogon country (Mali, 11th-18th century)

Afrique Archéologie Arts, 2015
Les méthodes analytiques de la biogéochimie s’appliquent depuis plusieurs dizaines d’années aux études archéologiques. L’une des questions majeures posées par cette approche reste la conservation des signaux biogéochimiques pendant la phase taphonomique.
Anne-France Maurer, Alain Person, Antoine Zazzo, Élise Dufour, Mathieu Sebilo, Vincent Balter, Florence Lecornec, Valery Zeitoun, Marc de Rafélis, Annette Schmidt, Rogier Bedaux   +10 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

BOOK REVIEW OF ALICE SEVOLD’S “THE LOVELY BONES” [PDF]

, 2015
Each human being has different life journey and experiences. In this life, sometimes there are times when people feel happiness, excitement, joy, the warmth of love, and perfection.
Dini, Emy Predina
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

First successful DNA isolation and profiling from bone using an approach that is non-destructive toward bone surface

Archives of Forensic Medicine and Criminology, 2016
Commonly used destructive DNA isolation techniques consist of pulverization which leads to the complete destruction of smaller bones or irreversible damage to larger bones through the cutting of extensive fragments.
Dominika Pluta, Arleta Lebioda, Anna Jonkisz, Tadeusz Dobosz   +3 more
doaj   +1 more source