COX-2 in Fracture Callus Chondro-Osseous Junction Osteoclasts Regulates Chondrocyte Hypertrophy and Callus Vasculogenesis. [PDF]
J Orthop ResABSTRACT Cyclooxygenase‐2 (COX‐2) activity is necessary for bone fracture healing to proceed normally. COX‐2 is encoded by Ptgs2 and is expressed by several cell types during fracture healing, suggesting that COX‐2 regulates multiple processes to affect fracture healing.
Teitelbaum M +4 more
europepmc +2 more sources
T cells heal bone fractures with help from the gut microbiome
The Journal of Clinical Investigation, 2023 Immune cells play an important functional role in bone fracture healing. Fracture repair is a well-choreographed process that takes approximately 21 days in healthy mice.
Rajeev Aurora, Matthew J. Silva
doaj +1 more source
Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose: To evaluate the effects of food restriction on fracture healing in growing rats. Methods: Sixty-eight male Wistar rats were assigned to two groups: (1) Control and (2) Dietary restriction. After weaning the dietary restricted animals were fed
Iara Inácio Botega +8 more
doaj +1 more source
Osteoarthritis after Extension Block Technique for the Bony Mallet Finger
Archives of Hand and Microsurgery, 2021 Purpose: The purpose of this study is to investigate osteoarthritis after treatment of bony mallet finger using the extension block method.Methods: A single institutional retrospective review identified 163 patients with bony mallet between January 2012 ...
S. Koh +5 more
semanticscholar +1 more source
Nandrolone decanoate appears to increase bone callus formation in young adult rats after a complete femoral fracture [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To evaluate the influence of nandrolone decanoate on fracture healing and bone quality in normal rats. Methods: Male rats were assigned to four groups (n=28/group): Control group consisting of animals without any intervention, Nandrolone ...
Ana Paula Franttini Garcia Moreno Guimarães +4 more
doaj +1 more source
Frontiers in Endocrinology, 2021 BackgroundOsteogenesis imperfecta (OI) type V is a rare form of OI which is often characterized by hyperplastic callus. Misdiagnosis is a possibility due to its rarity and because patients involved are mostly in adolescence, a predisposing age for ...
Ying Deng, Yanan Huo, Jinfeng Li
doaj +1 more source
Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]
, 2018 Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N. +3 more
core +1 more source
Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. [PDF]
PLoS ONE, 2015 Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis.
Vanessa Scanlon +6 more
doaj +1 more source
Human Mesenchymal Stromal Cell Sheet Enhances Allograft Repair in a Mouse Model
Scientific Reports, 2017 To determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum in a femoral allograft mouse model similar to fresh passaged (
Xifu Shang +8 more
doaj +1 more source
New technologies in rhinoplasty : a comprehensive workflow for computer-assisted planning and execution [PDF]
, 2019 Rhinoplasty in facial cleft patients is among the most challenging types of reconstructive facial surgery due to its variability Advances in 3-dimensional imaging enable improved preoperative assessment in rhinoplasty.
Codazzi +7 more
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