Results 21 to 30 of about 156,386 (240)

T cells heal bone fractures with help from the gut microbiome

open access: yesThe Journal of Clinical Investigation, 2023
Immune cells play an important functional role in bone fracture healing. Fracture repair is a well-choreographed process that takes approximately 21 days in healthy mice.
Rajeev Aurora, Matthew J. Silva
doaj   +1 more source

Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture [PDF]

open access: yesActa Cirúrgica Brasileira, 2019
Purpose: To evaluate the effects of food restriction on fracture healing in growing rats. Methods: Sixty-eight male Wistar rats were assigned to two groups: (1) Control and (2) Dietary restriction. After weaning the dietary restricted animals were fed
Iara Inácio Botega   +8 more
doaj   +1 more source

Nandrolone decanoate appears to increase bone callus formation in young adult rats after a complete femoral fracture [PDF]

open access: yesActa Cirúrgica Brasileira, 2017
Purpose: To evaluate the influence of nandrolone decanoate on fracture healing and bone quality in normal rats. Methods: Male rats were assigned to four groups (n=28/group): Control group consisting of animals without any intervention, Nandrolone ...
Ana Paula Franttini Garcia Moreno Guimarães   +4 more
doaj   +1 more source

Case Report: Hyperplastic Callus of the Femur Mimicking Osteosarcoma in Osteogenesis Imperfecta Type V

open access: yesFrontiers in Endocrinology, 2021
BackgroundOsteogenesis imperfecta (OI) type V is a rare form of OI which is often characterized by hyperplastic callus. Misdiagnosis is a possibility due to its rarity and because patients involved are mostly in adolescence, a predisposing age for ...
Ying Deng, Yanan Huo, Jinfeng Li
doaj   +1 more source

Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. [PDF]

open access: yesPLoS ONE, 2015
Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis.
Vanessa Scanlon   +6 more
doaj   +1 more source

Expression of Neurotrophins and Their Receptors Tropomyosin-related kinases (Trk) under Tension-stress during Distraction Osteogenesis [PDF]

open access: yes, 2006
The localization and expression of neurotrophins and their receptors during distraction osteogenesis was investigated in 72 male rat femurs (11 weeks old) to further clarify the concurrence of cellular and molecular events of new bone formation.
Aiga, Ayako   +6 more
core   +1 more source

Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]

open access: yes, 2018
Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N.   +3 more
core   +1 more source

Human Mesenchymal Stromal Cell Sheet Enhances Allograft Repair in a Mouse Model

open access: yesScientific Reports, 2017
To determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum in a femoral allograft mouse model similar to fresh passaged (
Xifu Shang   +8 more
doaj   +1 more source

The role of hypertrophic chondrocytes in regulation of the cartilage-to-bone transition in fracture healing

open access: yesBone Reports, 2022
Endochondral bone formation is an important pathway in fracture healing, involving the formation of a cartilaginous soft callus and the process of cartilage-to-bone transition.
Joe Kodama   +4 more
doaj  

Effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair

open access: yesBMC Musculoskeletal Disorders, 2022
Background To estimate the effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair in an animal model. Methods Five mm radial bone defect in length was made in 64 mature New Zealand rabbits and all animals
Weilong Diwu   +6 more
doaj   +1 more source

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