Results 21 to 30 of about 7,066 (201)

Case Report: Hyperplastic Callus of the Femur Mimicking Osteosarcoma in Osteogenesis Imperfecta Type V

open access: yesFrontiers in Endocrinology, 2021
BackgroundOsteogenesis imperfecta (OI) type V is a rare form of OI which is often characterized by hyperplastic callus. Misdiagnosis is a possibility due to its rarity and because patients involved are mostly in adolescence, a predisposing age for ...
Ying Deng, Yanan Huo, Jinfeng Li
doaj   +1 more source

Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. [PDF]

open access: yesPLoS ONE, 2015
Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis.
Vanessa Scanlon   +6 more
doaj   +1 more source

Human Mesenchymal Stromal Cell Sheet Enhances Allograft Repair in a Mouse Model

open access: yesScientific Reports, 2017
To determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum in a femoral allograft mouse model similar to fresh passaged (
Xifu Shang   +8 more
doaj   +1 more source

Paediatric pelvic fractures – an updated literature review

open access: yesANZ Journal of Surgery, Volume 92, Issue 12, Page 3182-3194, December 2022., 2022
Pelvic fractures in children secondary to trauma are rare and associated with multi‐system injuries. They differ from fractures in adults and therefore require different considerations in assessment and management. In our literature review, we reviewed the current evidence on the incidence, pathophysiology, assessment, management and complications of ...
Alexander T. M. Nguyen   +2 more
wiley   +1 more source

The role of hypertrophic chondrocytes in regulation of the cartilage-to-bone transition in fracture healing

open access: yesBone Reports, 2022
Endochondral bone formation is an important pathway in fracture healing, involving the formation of a cartilaginous soft callus and the process of cartilage-to-bone transition.
Joe Kodama   +4 more
doaj  

Effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair

open access: yesBMC Musculoskeletal Disorders, 2022
Background To estimate the effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair in an animal model. Methods Five mm radial bone defect in length was made in 64 mature New Zealand rabbits and all animals
Weilong Diwu   +6 more
doaj   +1 more source

Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34). [PDF]

open access: yesPLoS ONE, 2011
Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited.
Yongxin Ren   +7 more
doaj   +1 more source

Computed tomographic diagnosis of a fracture of the floor of the pelvis in a Thoroughbred foal

open access: yesEquine Veterinary Education, Volume 35, Issue 2, Page 82-86, February 2023., 2023
Summary This case report describes the clinical and diagnostic imaging findings, treatment and outcomes of a 15‐day‐old Thoroughbred foal referred for the evaluation of severe left hindlimb lameness of 8 days' duration. Radiographic examination of the left hindlimb and transcutaneous ultrasonographic examination of the pelvis were unremarkable.
Nicola Scilimati   +6 more
wiley   +1 more source

Unbiased gene expression analysis of the delayed fracture healing observed in Zucker diabetic fatty rats

open access: yesBone & Joint Research, 2023
Aims: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to
Jonghoo Sung   +7 more
doaj   +1 more source

Loss of Bcl-3 delays bone fracture healing through activating NF-κB signaling in mesenchymal stem cells

open access: yesJournal of Orthopaedic Translation, 2022
Background: Bone fracture healing is a postnatal regenerative process in which fibrocartilaginous callus formation and bony callus formation are important. Bony callus formation requires osteoblastic differentiation of MSCs.
Fuxiao Wang   +9 more
doaj  

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