High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model. [PDF]
Small animal studies have demonstrated significant high-dose recombinant parathyroid hormone1-34 (rPTH1-34) effects on intercalary allograft healing. Towards a human adjuvant therapy to decrease non-unions, we evaluated rPTH1-34 safety and efficacy in a ...
Kohei Nishitani+7 more
doaj +1 more source
Despite their significance for paleobiological interpretations, bite marks have been rarely reported in non-mammalian therapsids (NMT). Here we describe, for the first time, the occurrence of a tooth embedded in the snout of a gorgonopsian.
Julien Benoit+2 more
doaj +1 more source
Probiotic‐Based Materials as Living Therapeutics
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio+2 more
wiley +1 more source
Radiology of fractures: classification, healing and complications [PDF]
C
Gielen, Ingrid
core +1 more source
Alloxan-induced diabetes delays repair in a rat model of closed tibial fracture [PDF]
A closed fracture was performed on the left tibia of 3-month-old Wistar rats weighing 250 to 350 g that were either healthy (N = 24) or made diabetic with alloxan (N = 24) to investigate the effect of alloxan-induced diabetes on the course of bone ...
Amorim, F. P. L. G.+6 more
core +4 more sources
Recent research has shown that biodegradable metals based on zinc (Zn) may be used as guided bone regeneration (GBR) membrane materials. This study examines their viability from the standpoints of material science and biology, reports on the state of research on Zn‐based GBR membranes, and suggests specific development plans based on the potential and ...
Kai Chen+12 more
wiley +1 more source
Modulation of fixation stiffness from flexible to stiff in a rat model of bone healing
Background and purpose — Constant fixator stiffness for the duration of healing may not provide suitable mechanical conditions for all stages of bone repair.
Nicole Bartnikowski+8 more
doaj +1 more source
Histological Evaluation for the Use of β-Tricalcium Phosphate as a Bone Substitute in Accelerating Bone Healing: An Experimental Study on Rabbits [PDF]
Aims: The present study designed to assess the effects of a bone substitute consisting of β-Tricalcium Phosphate (β-TCP) on acceleration of bone healing of surgically created defects. Materials and Methods: Ten rabbits were included in the study.
Atalla F Rejab +2 more
doaj +1 more source
The role of peptides in bone healing and regeneration: A systematic review [PDF]
Background: Bone tissue engineering and the research surrounding peptides has expanded significantly over the last few decades. Several peptides have been shown to support and stimulate the bone healing response and have been proposed as therapeutic ...
A Au+250 more
core +2 more sources
The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan+16 more
wiley +1 more source