Results 101 to 110 of about 144,736 (256)

ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial.

The ETOP 10-16 BOOSTER study was a randomized phase II trial of osimertinib and bevacizumab therapy versus osimertinib therapy in patients with an acquired EGFR T790M mutation. The mechanisms of acquired resistance to osimertinib and bevacizumab have not
Coate, L., Finn, S.P., Dimopoulou, G., de Castro, J., Yeo, C.M., Britschgi, C., Sala, M.A., Soo, R.A., Provencio, M., Peters, S., Carcereny, E., Cho, B.C., Han, J.Y., Stahel, R.A., Dafni, U., Nadal, E., Vagenknecht, P., Kammler, R.   +17 more
core   +1 more source

Are booster lessons beneficial?

, 2020
A Thesis Submitted in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science (Honours) in Psychology, University of Regina. 89 p.Internet-delivered cognitive behaviour therapy (iCBT) has been found to be effective among post ...
Patterson, Taylor
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

29.21 S81-33180 Solid Rocket Booster (SRB) separation

, 1983
This image reflects the Solid Rocket Booster (SRB) separation, possibly for the STS-8 ...

core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Accessing the 'hidden job market' (Young Alumni Career Booster)

, 2018
In this webinar for final year students and young alumni, Rob Vague (Career Development Manager) outlines some techniques to access jobs which aren’t advertised.
Rob Vague
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Towards an empirical methodology for the measurement of the quality entrepreneur: the case of sevillian entrepreneurs [PDF]

Since the process of globalization increased its importance during the nineties, the entrepreneur's role in regional economic development is considered essential.
Liñán Alcalde, Francisco, Santos Cumplido, Francisco Javier   +1 more
core  

Longitudinal Immunological Analysis of Portuguese Healthcare Workers Across the COVID-19 Pandemic Reveals Differences in the Humoral Immune Response to Vaccines

Vaccines
Background: A vaccination programme against severe acute respiratory syndrome coronavirus 2 was initiated in Portugal in December 2020. In this study, we report the findings of a prospective cohort study implemented with the objective of monitoring ...
Luísa Vilela, Anabela Silva, Alberta Cruz, Madalena Sousa, Margarida Costa, Fernando Fonseca, Susana Campino, Taane G. Clark, Anabela Miranda   +8 more
doaj   +1 more source