Results 121 to 130 of about 144,736 (256)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Correlates of COVID-19 Vaccination Intentions and Booster Vaccination Intentions

open access: yes, 2022
The COVID-19 pandemic is a global public health crisis that has made a substantive contribution to excess global deaths in 2020 and 2021, and set to do so again in 2022.
Smith, Stephanie R   +3 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Safe booster starts

open access: yes, 1991
AE-1021; This circular provides steps to booster starting and how to reduce the need for booster ...
Maher, George G.
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Booster.

open access: yes, 1998
End of the previous footage on Booster. Then film on CERN : https://videos.cern.ch/record/1038936 in multiple languagespeople working, making ...

core  

NSLS-II Booster Acceptance Studies [PDF]

open access: yes, 2009
The NSLS-II is a state of the art 3 GeV synchrotron light source being developed at BNL. The injection system will consist of a 200 MeV linac and a 3 GeV booster synchrotron.
Fliller, R., III   +4 more
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Booster Akatemian kehittäminen [PDF]

open access: yes, 2016
Opinnäytetyön tarkoituksena oli kehittää Booster Akatemian konseptia. Opinnäytetyön ensimmäisenä tavoitteena oli perehtyä trainee-ohjelman rakentamiseen. Trainee-ohjelman rakentamisessa keskityttiin ohjelman sisältöön ja rakenteeseen.
Mäkiranta, Viivi
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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