Results 171 to 180 of about 99,102 (265)

Safety and Immunogenicity of a Sabin Strain-Based Inactivated Polio Vaccine: A Phase III, Randomized, Blinded, Positive-Control Clinical Trial in Infants Aged Two Months. [PDF]

Vaccines (Basel)
Zhang H, Chen Y, Xu B, Tang R, Wang Y, Hu J, Yang S, Wei M, Li G, Liang Q.   +9 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Immunosenescence and cytomegalovirus-associated immune signatures on severe acute respiratory syndrome coronavirus 2 booster responses. [PDF]

J Gerontol A Biol Sci Med Sci
Reina-Alfonso I, Álvarez-Heredia P, Vallejo-Bermúdez IM, Navas-Romo A, Espinar-García M, Hassouneh F, Pérez AB, Tarazona R, Solana R, Batista-Duharte A, Molina J, Pera A.   +11 more
europepmc   +1 more source

Tetanus and Diphtheria Boosters

Clinical Infectious Diseases, 2020
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Absence of autoantibodies linked to cancer and autoimmune disorders 26 weeks after BNT162b2 boosting in CoronaVac- primed individuals. [PDF]

Hum Vaccin Immunother
Mat Yassim AS, Mohd Hisham AA, Mohd Rosdan BS, Tan TM, Anuar ND, Mohamed Hashim EK, Norazmi MN.   +6 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Using the Diffusion of Innovation Theory to Understand COVID-19 Booster Hesitancy in Adults. [PDF]

Int J Environ Res Public Health
Luck CC, Bass SB, Singley KJ, Hoadley A, Paulus K, Askew-Shabazz I, Cabey W, Abuhillo M, Kelly PJA, Rincon M, Gardiner H.   +10 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Association Between Socio-Political and Economic Factors and COVID-19 Vaccination Uptake: US-Mexico Border Study. [PDF]

Epidemiologia (Basel)
Koumi K, Jeon S, Lee YF.
europepmc   +1 more source