Results 181 to 190 of about 144,736 (256)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The impact of ethnicity on longitudinal humoral and cellular immune responses to SARS-CoV-2 booster vaccination. [PDF]

Sci Rep
Martin CA, Nazareth J, Teece L, Pan D, Scott S, Jarkhi A, Das M, Bryant L, George N, Gohar M, Renals V, Wenn V, Vail D, Karia A, Moss P, Willett BJ, Tattersall A, Hallis B, Otter AD, Rowe C, Haldar P, Cooper A, Pareek M.   +22 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Impact of ABO Blood System on Immunogenicity and Vaccine Efficacy of COVID-19 Booster Vaccination-A Population-Based Study of 3066 Individuals. [PDF]

Influenza Other Respir Viruses
Sieghart D, Jordakieva G, Dürrschmid C, Hana CA, Tran LV, Heinz LX, Haslacher H, Zlesak M, Marzoner V, Nasztl P, Piccini G, Manenti A, Montomoli E, Jorda A, Fedrizzi C, Hasenoehrl T, Zdravkovic A, Anderle K, Wiedermann U, Drapalik S, Steinbrecher H, Bergmann F, Firbas C, Wagner B, Leonardi M, Pierleoni G, Ballini M, Benincasa L, Marchi S, Trombetta CM, Perkmann T, Crevenna R, Zeitlinger M, Bonelli M, Aletaha D, Radner H.   +35 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Longevity and Magnitude of Antibody Responses After Homologous and Heterologous COVID-19 Booster Vaccinations in Bangladesh. [PDF]

Vaccines (Basel)
Akhtar M, Islam MR, Khan ZH, Akter A, Tauheed I, Ahmed T, Khan II, Amin MA, Khaton F, Khanam F, Islam MT, Biswas PK, Rashid R, Rashid MM, Hossain MZ, Alam AN, Alamgir ASM, Ryan ET, Banu S, Shirin T, Chowdhury F, Khan AI, Bhuiyan TR, Qadri F.   +23 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Association between SARS-CoV-2 booster vaccination and hospitalisation and/or death due to COVID-19 in adults with immune-mediated inflammatory diseases: nested case-control study using linked primary-care, hospitalisation and mortality data from England. [PDF]

RMD Open
Kukreja NS, Nakafero G, Abhishek A.
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The value of CMR-derived left atrial strain parameters in differential diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy. [PDF]

Quant Imaging Med Surg
Jin Y, Shao X, Zhang Y, Zhang W, Wang K, Li S, Jin H, Huang H.   +7 more
europepmc   +1 more source