Results 141 to 150 of about 2,284,562 (345)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Spatial integration in European cross-border metropolitan regions: A comparative approach [PDF]
This article analyses the process of spatial integration in ten European cross-border metropolitan regions. On the basis of three indicators, relating to flows of cross-border commuters, gross domestic product and the housing market, it suggests that ...
DECOVILLE Antoine +3 more
core +1 more source
Borders Manifest: Racializing the Nicaraguan Refugee in Costa Rica [PDF]
, 2019 I look to border responses of North American countries as refugees and migrants move across them to argue that border responses racialize the foreign other in receiving countries.
Twidwell, Theodore B.
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
IEEE AccessUnder-five mortality remains a significant public health challenge in the Central African Republic (CAR), yet research on the region-specific determinants of this issue is limited.
Ali Satty +7 more
doaj +1 more source
What Does the NAEP Tell Us About Student Achievement in Arkansas? [PDF]
, 2005 This brief discusses the most recent and historical NAEP data in math, science, reading, and writing. Arkansas’ NAEP results are compared to national and border state averages.
Barnett, Joshua H., Ritter, Gary W.
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
No. 73: Informal Entrepreneurship and Cross-Border Trade in Maputo, Mozambique [PDF]
, 2016 Cross-border trading is an essential part of Mozambique’s informal economy, with the traders playing a key role in supplying commodities that are in scarce supply nationwide.
Chikanda, Abel, Raimundo, Inês
core +1 more source