Results 101 to 110 of about 55,498 (271)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Case Management of Imported Crimean-Congo Hemorrhagic Fever, Senegal, July 2023
Emerging Infectious DiseasesWe report an imported Crimean-Congo hemorrhagic fever case in Senegal. The patient received PCR confirmation of virus infection 10 days after symptom onset. We identified 46 patient contacts in Senegal; 87.7% were healthcare professionals. Strengthening
Youssou Bamar Gueye +9 more
doaj +1 more source
First molecular evidence of border disease virus in wild boars in Turkey. [PDF]
Vet Res Commun, 2022 Saltik HS, Kale M, Atli K.
europepmc +1 more source
Identification of «Border Disease» in sheep in France [PDF]
, 1984 La maladie de Border ou « Border disease » (B.D.) a été diagnostiquée dans un élevage comprenant 150 brebis, en Ardèche (France). Le tableau clinique comprenait des avortements, des anomalies de la toison, des déformations du squelette, des symptômes ...
Parodi, A.L. +6 more
core +1 more source
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Border disease: an under-appreciated threat to flock health and productivity?
, 2018 Border disease is a syndrome of sheep caused by pestiviral infection, most commonly by border disease virus (BDV), but also by bovine viral diarrhoea virus (BVDV). Border disease results in a varied spectrum of clinical signs, but most commonly increased
Gascoigne, Emily +5 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato +27 more
wiley +1 more source
Discover Global SocietyThe Coronavirus Disease 2019 (COVID-19) pandemic prompted governments worldwide to enforce biosecurity measures such as border closures, lockdowns, and testing protocols to contain the virus.
Blessing Mukuruva
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao +9 more
wiley +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source