Results 81 to 90 of about 55,498 (271)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Diagnosis of Border Disease Virus (BDV) infection in three Egyptian governorates among sheep flocks during 2025 [PDF]

Benha Veterinary Medical Journal
Pestivirus infections, especially Border Disease Virus (BDV), have serious consequences for sheep health and the agricultural economy; they are a major implication cause of reproductive and economic losses in small ruminants.
rania elmohamdy, yasser abdelhafeiz, Haitham Albaqly, Abdel-Aziz Saker   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Prevalence and Identification of Infectious Abortion Pathogens in Sheep Flocks of North Khorasan, Iran [PDF]

Archives of Razi Institute
Abortion is one of the main causes of reproduction losses in small ruminant’s flocks in the world. Infection with the agents including Toxoplasma gondii, Campylobacter spp., Chlamydia abortus, and Coxiella burnetii frequently occurs worldwide.
Hossein Esmaeili, hassan Ghasemifard, mona hamedi, mahyar sharifan, pejman bahari   +4 more
doaj   +1 more source

Spatial Associations Between Land Use and Infectious Disease: Zika Virus in Colombia

, 2020
Land use boundaries represent human–physical interfaces where risk of vector-borne disease transmission is elevated. Land development practices, coupled with rural and urban land fragmentation, increases the likelihood that immunologically naï ...
Joshua S. Weinstein, Timothy F. Leslie, Michael E. von Fricken   +2 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Detection of border disease virus in sheep fetuses by immunoperoxidase [PDF]

Eurasian Journal of Veterinary Sciences
Aim: The purpose of the present study was to investigate pestiviral antigen in sheep fetuses in Konya. Materials and Methods: Totally 170 samples (liver, lung, lymph, spleen, and brain) from 34 sheep fetuses were investigated to determine the presence of
Sibel Yavru, Oğuzhan Avcı, Kamil Atlı   +2 more
doaj  

Sero Survey of Foot and Mouth Disease Virus Infection in Cattle Crossing Some Major Border States in Northwestern Nigeria

Folia Veterinaria, 2017
Foot and mouth disease (FMD) poses a major constraint to international trade in animals and animal products in sub-Saharan Africa. A retrospective and serological survey was conducted in two major Border States of Sokoto and Kebbi in north-western ...
Babangida D., Ibrahim A. A., Oladayo F. O., Magaji A. A., Alkali B. R., Jibril A. H.   +5 more
doaj   +1 more source

The epidemiology of foot-and-mouth disease in the kingdom of Bhutan

, 2011
Foot-and-mouth disease (FMD) is a highly infectious viral disease of all cloven-hoofed animals. It can have a significant impact on the livelihood of livestock owners, especially in developing nations such as Bhutan.
Dukpa, Kinzang
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source