Results 11 to 20 of about 63,008 (218)

High-Yield Expression of Arylmalonate Decarboxylase in Escherichia coli Through High-Cell-Density Cultivation Strategies. [PDF]

open access: yesChembiochem
Optimized high‐cell‐density cultivation in the DASGIP® multibioreactor enabled a 30‐fold increase in soluble expression of arylmalonate decarboxylase (BbAMDase) from Bordetella bronchiseptica in E. coli BL21 (DE3). Linear glucose and optimized glycerol feeding strategies during induction ensured stable, scalable enzyme production.
Gerstenberger J   +3 more
europepmc   +2 more sources

Bordetella spp. utilize the type 3 secretion system to manipulate the VIP/VPAC2 signaling and promote colonization and persistence of the three classical Bordetella in the lower respiratory tract

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionBordetella are respiratory pathogens comprised of three classical Bordetella species: B. pertussis, B. parapertussis, and B. bronchiseptica. With recent surges in Bordetella spp.
Nicholas J. First   +5 more
doaj   +1 more source

Improving specificity of Bordetella pertussis detection using a four target real-time PCR. [PDF]

open access: yesPLoS ONE, 2017
The incidence of whooping cough, a contagious respiratory disease caused by Bordetella pertussis, is on the rise despite existing vaccination programmes.
Helena Martini   +4 more
doaj   +1 more source

Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.

open access: yesmSphere, 2022
Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard ...
Monica C. Gestal   +3 more
doaj   +1 more source

Outer-Membrane-Vesicle-Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]

open access: yes, 2018
Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Bartel, Erika Belén   +8 more
core   +3 more sources

Increase in pertussis cases along with high prevalence of two emerging genotypes of Bordetella pertussis in Perú, 2012 [PDF]

open access: yes, 2016
As has occurred in many regions worldwide, in 2012 the incidence of pertussis increased in Perú. This epidemiologic situation has been associated with a waning vaccine-induced immunity and the adaptation of Bordetella pertussis to vaccine-induced ...
Bailon, H   +3 more
core   +3 more sources

A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex

open access: yesVaccines, 2016
Serosurveillance and seroprevalence studies are an essential tool to monitor vaccine-preventable diseases. We have developed a magnetic bead-based pentaplex immunoassay (MIA) for the simultaneous detection of IgG antibodies against diphtheria toxin (DT),
Raissa Nadège Caboré   +2 more
doaj   +1 more source

Bordetella pertussis

open access: yesMicrobiology Spectrum, 2016
ABSTRACTPertussis is a highly infectious vaccine-preventable cough illness that continues to be a significant source of morbidity and mortality around the world. The majority of human illness is caused byBordetella pertussis, and some is caused byBordetella parapertussis.Bordetellais a Gram-negative, pleomorphic, aerobic coccobacillus.
Delma J, Nieves, Ulrich, Heininger
openaire   +2 more sources

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]

open access: yes, 2017
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora   +22 more
core   +1 more source

Impact of nutrient medium composition on protein profiling of Bordetella spp. [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия
Objective. To perform comparative analysis of Bordetella protein profiling data and their dependence on various nutrient media. Materials and Methods. This prospective open single-center study, the protein profiles of B. pertussis, B.
Vidmanova M.V.   +5 more
doaj   +1 more source

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