Results 1 to 10 of about 15,118 (69)

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Disruption of the blood–brain barrier contributes to neurobehavioral changes observed in rheumatic heart disease

Animal Models and Experimental Medicine, EarlyView.
Sydenham's chorea (SC) is the neurological manifestation associated with acute rheumatic fever (ARF), triggered by a group A streptococcal (GAS) infection. Anti‐GAS antibodies cross‐reacting with tissue proteins are implicated in the development of neurological changes. In this study, using an animal model, we demonstrate that a compromised blood–brain
Rukshan Ahamed Mohamed Rafeek, Riya Thapa, Samarjeet Saluja, Bipandeep Banga, David McMillan, Kadaba Sri Sriprakash, Nicholas M. Andronicos, Adam Hamlin, Natkunam Ketheesan   +8 more
wiley   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Clinical progress note: Pertussis

Journal of Hospital Medicine, EarlyView.
Abstract Pertussis, commonly known as whooping cough, is a vaccine‐preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of hospitalization and ...
Samantha Hanna, Nicole Samies
wiley   +1 more source

Epidemiological and clinical profile of viral respiratory infections in children under 5 years at pre‐ and post‐COVID‐19 era in Praia, Cabo Verde

Tropical Medicine &International Health, EarlyView.
Abstract Background The coronavirus disease‐19 (COVID‐19) pandemic has affected global health, influencing the prevalence of different respiratory pathogens. The aim of this study is to evaluate the distribution of agents causing acute respiratory infections in children under 5 years old before and after the COVID‐19 pandemic in Praia, Cabo Verde, and ...
Wilson Correia, Roberto Dorta‐Guerra, Mitza Sanches, Basilio Valladares, Isabel Inês M. de Pina‐Araújo, Emma Carmelo   +5 more
wiley   +1 more source

Case Report: Hematopoietic Stem Cell Transplantation to Treat Severe Acquired Aplastic Anemia in a Pediatric Kidney Transplant Recipient

Pediatric Transplantation, Volume 29, Issue 5, August 2025.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė, Goda Elizabeta Vaitkevičienė, Karolis Ažukaitis, Augustina Jankauskienė, Jelena Rascon   +4 more
wiley   +1 more source

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source

Humoral Immunity to Measles, Mumps, Rubella, Diphtheria, Tetanus and Pertussis After Cancer Treatment in Children

Cancer Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background Treatment for pediatric malignancies has distinct effects on the immune system. Aims Our aim was to measure humoral immunity to measles, mumps and rubella (MMR), and diphtheria, tetanus and acellular pertussis (DTaP) vaccines after pediatric cancer treatment.
Susanna Sundell, Miia Laine, Liisa Järvelä, Ville Peltola, Tytti Vuorinen, Päivi Lähteenmäki, Linnea Schuez‐Havupalo   +6 more
wiley   +1 more source

Clinical and Epidemiological Insights into a Parainfluenza Virus Type 3 Outbreak in Multiple Myeloma Patients

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT Human parainfluenza virus type 3 (HPIV‐3) can be responsible for mild to severe respiratory infections and hospital epidemics. We investigated an outbreak in a hematology unit. Respiratory viruses were screened using multiplex PCR. HPIV‐3 quantification and whole‐genome sequencing were performed on HPIV‐3 positive respiratory samples. Clinical
Sarah Timsit, Guillaume Mellon, Nathalie Forgeard, Séverine Mercier‐Delarue, Nadia Mahjoub, Victor Euzen, Stéphanie Harel, Dikelele Elessa, Nathalie Osinski, Elise Diaz, Bruno Royer, Bertrand Arnulf, Maud Salmona, Jérôme Legoff   +13 more
wiley   +1 more source

Investigation of the Correlation Between ELISA and Serum Amyloid A in the Diagnosis of Bordetella bronchiseptica in Dogs

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
A study in Van, Turkey examined Bordetella bronchiseptica in shelter dogs using ELISA and PCR. Overall, 12% of blood samples tested positive. Serum amyloid A (SAA) levels were significantly elevated in positive cases, suggesting SAA could be a useful diagnostic marker for this chronic respiratory disease‐causing bacterial pathogen.
Kadir Akar, Gökçenur Sanioğlu Gölen, İsmail Hakkı Ekin   +2 more
wiley   +1 more source