Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding. [PDF]
Protein SciAbstract Disulphide bonds (Dsbs) are essential for the folding, stability, and function of many secreted and membrane‐associated proteins in bacteria. In Gram‐negative species, these bonds are introduced by the Dsb enzyme family, with DsbA acting as the primary thiol oxidase.
Penning S +9 more
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Microbiology Spectrum, 2016 ABSTRACTPertussis is a highly infectious vaccine-preventable cough illness that continues to be a significant source of morbidity and mortality around the world. The majority of human illness is caused byBordetella pertussis, and some is caused byBordetella parapertussis.Bordetellais a Gram-negative, pleomorphic, aerobic coccobacillus.
Delma J, Nieves, Ulrich, Heininger
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Severe pertussis infection in infants less than 6 months of age: clinical manifestations and molecular characterization [PDF]
, 2017 We conducted a study to determine the main traits of pertussis among unimmunized infants less than 6 months of age. From August 2012 to March 2015, 141 nasopharyngeal aspirates (NPAs) were collected from infants with respiratory symptoms attending 2
Buttinelli, Gabriele +12 more
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Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]
, 2020 The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul +8 more
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Membrane vesicles derived from Bordetella bronchiseptica: Active constituent of a new vaccine against infections caused by this pathogen [PDF]
, 2018 Bordetella bronchiseptica, a Gram-negative bacterium, causes chronic respiratory tract infections in a wide variety of mammalian hosts, including humans (albeit rarely).
Bartel, Erika Belén +5 more
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Bordetella parapertussis Survives inside Human Macrophages in Lipid Raft-Enriched Phagosomes [PDF]
, 2014 Bordetella parapertussis is a human pathogen that causes whooping cough. The increasing incidence of B. parapertussis has been attributed to the lack of cross protection induced by pertussis vaccines. It was previously shown that B. parapertussis is able
Gorgojo, Juan Pablo +2 more
core +3 more sources
BMC Infectious Diseases, 2017 Background Pertussis, a vaccine preventable disease, is still responsible of significant morbidity and mortality around the world, mostly in newborns.
Khalid Katfy +8 more
doaj +1 more source
Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]
, 2017 Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita +13 more
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Protocol for aerosolization challenge of mice with Bordetella pertussis
STAR Protocols, 2023 Summary: Bordetella pertussis causes whooping cough and is transmitted via respiratory droplets. Here, we present a protocol to challenge mice with Bordetella pertussis.
Graham Bitzer +3 more
doaj +1 more source
Increase in pertussis cases along with high prevalence of two emerging genotypes of Bordetella pertussis in Perú, 2012 [PDF]
, 2016 As has occurred in many regions worldwide, in 2012 the incidence of pertussis increased in Perú. This epidemiologic situation has been associated with a waning vaccine-induced immunity and the adaptation of Bordetella pertussis to vaccine-induced ...
Bailon, H +3 more
core +3 more sources