Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul +8 more
core +1 more source
Membrane vesicles derived from Bordetella bronchiseptica: Active constituent of a new vaccine against infections caused by this pathogen [PDF]
Bordetella bronchiseptica, a Gram-negative bacterium, causes chronic respiratory tract infections in a wide variety of mammalian hosts, including humans (albeit rarely).
Bartel, Erika Belén +5 more
core +2 more sources
Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]
Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita +13 more
core +1 more source
Background Pertussis, a vaccine preventable disease, is still responsible of significant morbidity and mortality around the world, mostly in newborns.
Khalid Katfy +8 more
doaj +1 more source
Protocol for aerosolization challenge of mice with Bordetella pertussis
Summary: Bordetella pertussis causes whooping cough and is transmitted via respiratory droplets. Here, we present a protocol to challenge mice with Bordetella pertussis.
Graham Bitzer +3 more
doaj +1 more source
Bordetella parapertussis Survives inside Human Macrophages in Lipid Raft-Enriched Phagosomes [PDF]
Bordetella parapertussis is a human pathogen that causes whooping cough. The increasing incidence of B. parapertussis has been attributed to the lack of cross protection induced by pertussis vaccines. It was previously shown that B. parapertussis is able
Gorgojo, Juan Pablo +2 more
core +3 more sources
Pertussis post-exposure prophylaxis among household contacts: a cost-utility analysis. [PDF]
BACKGROUND: Recent pertussis outbreaks have prompted re-examination of post-exposure prophylaxis (PEP) strategies, when immunization is not immediately protective.
Crowcroft, Natasha S +3 more
core +2 more sources
Bacterial outer membrane vesicles and vaccine applications [PDF]
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +2 more sources
Pertussis, caused by Bordetella pertussis, is an important cause of morbidity and mortality in newborn and infancy. Pertussis is diagnosed clinically. It is confirmed by microbiological-serological tests. In recent years, polymerase chain reaction method
Kürşad Kemal Kara +4 more
doaj +1 more source
Increase in pertussis cases along with high prevalence of two emerging genotypes of Bordetella pertussis in Perú, 2012 [PDF]
As has occurred in many regions worldwide, in 2012 the incidence of pertussis increased in Perú. This epidemiologic situation has been associated with a waning vaccine-induced immunity and the adaptation of Bordetella pertussis to vaccine-induced ...
Bailon, H +3 more
core +3 more sources

