Pertussis, caused by Bordetella pertussis, is an important cause of morbidity and mortality in newborn and infancy. Pertussis is diagnosed clinically. It is confirmed by microbiological-serological tests. In recent years, polymerase chain reaction method
Kürşad Kemal Kara +4 more
doaj +1 more source
Pertussis post-exposure prophylaxis among household contacts: a cost-utility analysis. [PDF]
BACKGROUND: Recent pertussis outbreaks have prompted re-examination of post-exposure prophylaxis (PEP) strategies, when immunization is not immediately protective.
Crowcroft, Natasha S +3 more
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Bacterial outer membrane vesicles and vaccine applications [PDF]
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +2 more sources
Bordetella holmesii, an emerging pathogen, can be misidentified as Bordetella pertussis by routine polymerase chain reaction (PCR). In some reports, up to 29% of the patients diagnosed with pertussis have in fact B.
Laure F Pittet +8 more
doaj +1 more source
Secretion of Pertussis Toxin from Bordetella pertussis [PDF]
Production and secretion of pertussis toxin (PT) is essential for the virulence of Bordetella pertussis. Due to the large oligomeric structure of PT, transport of the toxin across bacterial membrane barriers represents a significant hurdle that the bacteria must overcome in order to maintain pathogenicity.
openaire +3 more sources
Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients. [PDF]
Correlates of protection (CoPs) against the highly contagious respiratory disease whooping cough, caused by Bordetella pertussis, remain elusive. Characterizing the antibody response to this pathogen is essential towards identifying potential CoPs. Here,
Bonačić Marinović, Axel A. +11 more
core +7 more sources
Bordetella pertussis infection [PDF]
Marco P. Barros Pinto
openaire +3 more sources
Outer-Membrane-Vesicle-Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]
Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Bartel, Erika Belén +8 more
core +3 more sources
Correction to "Identification of the Minimum Region of Bordetella pertussis Vag8 Required for Interaction With C1 Inhibitor". [PDF]
europepmc +3 more sources
Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal +94 more
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