Results 21 to 30 of about 17,381 (199)

Bordetella spp. utilize the type 3 secretion system to manipulate the VIP/VPAC2 signaling and promote colonization and persistence of the three classical Bordetella in the lower respiratory tract

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionBordetella are respiratory pathogens comprised of three classical Bordetella species: B. pertussis, B. parapertussis, and B. bronchiseptica. With recent surges in Bordetella spp.
Nicholas J. First, Jose Pedreira-Lopez, Manuel R. F. San-Silvestre, Katelyn M. Parrish, Xiao-Hong Lu, Monica C. Gestal   +5 more
doaj   +1 more source

Bordetella pertussis and Bordetella parapertussis: two immunologically distinct species [PDF]

Infection and Immunity, 1993
Bordetella pertussis and Bordetella parapertussis are closely related species. Both are responsible for outbreaks of whooping cough in humans and produce similar virulence factors, with the exception of pertussis toxin, specific to B. pertussis. Current pertussis whole-cell vaccine will soon be replaced by acellular vaccines containing major adhesins ...
N, Khelef, B, Danve, M J, Quentin-Millet, N, Guiso   +3 more
openaire   +2 more sources

Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence

Frontiers in Cellular and Infection Microbiology, 2021
The Bordetella genus is divided into two groups: classical and non-classical. Bordetella pertussis, Bordetella bronchiseptica and Bordetella parapertussis are known as classical bordetellae, a group of important human pathogens causing whooping cough or ...
Laurence Don Wai Luu, Ling Zhong, Sandeep Kaur, Mark J. Raftery, Ruiting Lan   +4 more
doaj   +1 more source

Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.

mSphere, 2022
Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard ...
Monica C. Gestal, Laura K. Howard, Kalyan K. Dewan, Eric T. Harvill   +3 more
doaj   +1 more source

Pertussis among patients with clinically compatible illness in the Amhara Regional State, Ethiopia

International Journal of Infectious Diseases, 2021
Background: Pertussis is an acute respiratory tract disease caused by Bordetella pertussis. In 2014, 24.1 million pertussis cases, resulting in 160,700 deaths, were estimated to have occurred worldwide.
Solomon Taye, Zemene Tigabu, Debasu Damtie, Gizachew Yismaw, Clinton Moodley, Mark P. Nicol, Belay Tessema, Baye Gelaw, Feleke Moges   +8 more
doaj   +1 more source

A newly discovered Bordetella species carries a transcriptionally active CRISPR-Cas with a small Cas9 endonuclease. [PDF]

BMC Genomics, 2015
Background Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (cas) are widely distributed among bacteria.
Ivanov YV, Shariat N, Register KB, Linz B, Rivera I, Hu K, Dudley EG, Harvill ET.   +7 more
europepmc   +2 more sources

The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]

PLoS ONE, 2012
Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
doaj   +1 more source

Biological Properties of Lipopolysaccharides from Bordetella Species [PDF]

Journal of General Microbiology, 1990
Biological activities of lipopolysaccharides (LPS) extracted from Bordetella pertussis, B. parapertussis and B. bronchiseptica were compared with those of Escherichia coli LPS. The LPS preparations from B. pertussis showed biological activities comparable to those of E. coli LPS in terms of lethal toxicity in galactosamine-sensitized mice, pyrogenicity
M, Watanabe, H, Takimoto, Y, Kumazawa, K, Amano   +3 more
openaire   +2 more sources

A comprehensive resource for Bordetella genomic epidemiology and biodiversity studies

, 2022
The genus Bordetella includes bacteria that are found in the environment and/or associated with humans and other animals. A few closely related species, including Bordetella pertussis, are human pathogens that cause diseases such as whooping cough. Here,
Bouchez, Valérie, Muehle, E, Bridel, Sébastien, Toubiana, J, Brisse, Sylvain, Bridel, S, Brancotte, B, Hauck, Sofia, Landier, Annie, Maiden, Martin, Landier, A, Jolley, Ka, Guillot, S, Hauck, S, Toubiana, Julie, Brisse, S, Bouchez, V, Brancotte, Bryan, Guillot, Sophie, Armatys, Nathalie, Mühle, Estelle, Maiden, Martin C. J., Armatys, N, Jolley, Keith A., Maiden, Martin CJ, Jolley, Keith   +25 more
core   +1 more source

Virulence factor secretion and translocation by Bordetella species [PDF]

Current Opinion in Microbiology, 2009
Here we review the Bordetella virulence secretome with an emphasis on factors that translocate into target cells. Recent advances in understanding the functions of adenylate cyclase toxin, a type 1 secretion system (T1SS) substrate, and pertussis toxin, a type IV secretion system (T4SS) substrate, are briefly described and a compilation of additional ...
Ruchi, Shrivastava, Jeff F, Miller
openaire   +2 more sources