Results 11 to 20 of about 27,791 (211)

Bordetella Adenylate Cyclase-Hemolysin Toxins

Toxins, 2017
Adenylate cyclase-hemolysin toxin is secreted and produced by three classical species of the genus Bordetella: Bordetella pertussis, B. parapertussis and B. bronchiseptica.
Nicole Guiso
doaj   +3 more sources

Virulence factor secretion and translocation by Bordetella species [PDF]

Current Opinion in Microbiology, 2009
Here we review the Bordetella virulence secretome with an emphasis on factors that translocate into target cells. Recent advances in understanding the functions of adenylate cyclase toxin, a type 1 secretion system (T1SS) substrate, and pertussis toxin, a type IV secretion system (T4SS) substrate, are briefly described and a compilation of additional ...
Ruchi, Shrivastava, Jeff F, Miller
openaire   +4 more sources

Dissecting human T cell responses against Bordetella species. [PDF]

The Journal of experimental medicine, 1988
To identify the minimal structures that may be important for the creation of a synthetic and/or recombinant vaccine against whooping cough, human T cell clones were obtained against Bordetella antigens. Cloned peripheral blood T lymphocytes from an immune donor were grown in IL-2 and tested for proliferation in response to inactivated Bordetella ...
M T, De Magistris, M, Romano, S, Nuti, R, Rappuoli, A, Tagliabue   +4 more
openaire   +4 more sources

Isolation of Bordetella species from unusual infection sites

JMM Case Reports, 2015
Introduction: Bordetella hinzii has been isolated mainly from respiratory specimens and from blood of immunocompromised patients, and Bordetella trematum from ear infections or leg, arm and ankle wounds and from diabetic foot ulcers. Bordetella holmesii is instead associated with bactaeremia in
Marisa Almuzara, Claudia Barberis, Germán M. Traglia, Gabriela Sly, Adriana Procopio, Viviana Vilches, Maria Soledad Ramírez, Ángela Famiglietti, Carlos Vay   +8 more
openaire   +4 more sources

Bordetella spp. utilize the type 3 secretion system to manipulate the VIP/VPAC2 signaling and promote colonization and persistence of the three classical Bordetella in the lower respiratory tract

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionBordetella are respiratory pathogens comprised of three classical Bordetella species: B. pertussis, B. parapertussis, and B. bronchiseptica. With recent surges in Bordetella spp.
Nicholas J. First, Jose Pedreira-Lopez, Manuel R. F. San-Silvestre, Katelyn M. Parrish, Xiao-Hong Lu, Monica C. Gestal   +5 more
doaj   +1 more source

Bordetella pertussis and Bordetella parapertussis: two immunologically distinct species [PDF]

Infection and Immunity, 1993
Bordetella pertussis and Bordetella parapertussis are closely related species. Both are responsible for outbreaks of whooping cough in humans and produce similar virulence factors, with the exception of pertussis toxin, specific to B. pertussis. Current pertussis whole-cell vaccine will soon be replaced by acellular vaccines containing major adhesins ...
N, Khelef, B, Danve, M J, Quentin-Millet, N, Guiso   +3 more
openaire   +2 more sources

Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]

, 2020
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul, Hannet, Irene, Hansen, Glen, Leber, Amy L., Lisby, Jan Gorm, Pareja, Josep, Relich, Ryan F., Schneider, Uffe Vest, Young, Stephen   +8 more
core   +1 more source

Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence

Frontiers in Cellular and Infection Microbiology, 2021
The Bordetella genus is divided into two groups: classical and non-classical. Bordetella pertussis, Bordetella bronchiseptica and Bordetella parapertussis are known as classical bordetellae, a group of important human pathogens causing whooping cough or ...
Laurence Don Wai Luu, Ling Zhong, Sandeep Kaur, Mark J. Raftery, Ruiting Lan   +4 more
doaj   +1 more source

Characterization of fimbrial subunits from Bordetella species [PDF]

Microbial Pathogenesis, 1987
Using antisera raised against serotype 2 and 3 fimbrial subunits from Bordetella pertussis, serologically related polypeptides were detected in Bordetella bronchiseptica, Bordetella parapertussis and Bordetella avium strains. The two B. pertussis fimbrial subunits, and three of the serologically related B.
Mooi, FRrivm, van der Heide, HGJrivm, ter Avest, AR, Welinder, KG, Livey, I, van der Zeijst, BAM, Gaastra, W   +6 more
openaire   +4 more sources

Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.

mSphere, 2022
Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard ...
Monica C. Gestal, Laura K. Howard, Kalyan K. Dewan, Eric T. Harvill   +3 more
doaj   +1 more source